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ELM:LIG_SH2_III (24 hits)
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Index
Epidermal growth factor receptor
Proto-oncogene tyrosine-protein kinase Src
Receptor tyrosine-protein kinase erbB-2
Tyrosine-protein kinase ABL1
Tyrosine-protein kinase JAK1
Tyrosine-protein kinase JAK2
Tyrosine-protein kinase JAK2
(Mus)
Tyrosine-protein kinase JAK3
Tyrosine-protein kinase Lck
Tyrosine-protein kinase Lyn
Tyrosine-protein kinase Lyn
(Mus)
Tyrosine-protein kinase SYK
Motif
Protein
Start
End
Switch Type
Switch Subtype
Switch description
Information
Evidence
Epidermal growth factor receptor -
EGFR
-  
Homo sapiens
LIG_SH2_III
EGFR_HUMAN
1008
1024
Binary
Physicochemical compatibility
Phosphorylation of Y1016 in the SH2-binding motif of
Epidermal growth factor receptor (EGFR)
induces binding to the
Signal transducer and activator of transcription 6 (STAT6)
protein.
details
Inferred
Proto-oncogene tyrosine-protein kinase Src -
SRC
-  
Homo sapiens
LIG_SH2_III
EGFR_HUMAN
1008
1024
Binary
Physicochemical compatibility
Phosphorylation of Y1016 in the SH2-binding motif of
Epidermal growth factor receptor (EGFR)
induces binding to the
Signal transducer and activator of transcription 6 (STAT6)
protein.
details
Inferred
LIG_SH2_III
EGFR_HUMAN
1008
1024
Binary
Physicochemical compatibility
Phosphorylation of Y1016 in the SH2-binding motif of
Epidermal growth factor receptor (EGFR)
induces binding to the
Signal transducer and activator of transcription 6 (STAT6)
protein.
details
Inferred
LIG_SH2_III
STA5A_HUMAN
686
702
Binary
Physicochemical compatibility
Phosphorylation of Y694 in the SH2-binding motif of
Signal transducer and activator of transcription 5A (STAT5A)
induces binding to the
Signal transducer and activator of transcription 5B (STAT5B)
protein.
details
Inferred
LIG_SH2_III
STA5A_HUMAN
686
702
Binary
Physicochemical compatibility
Phosphorylation of Y694 in the SH2-binding motif of
Signal transducer and activator of transcription 5A (STAT5A)
induces binding to the
Signal transducer and activator of transcription 5B (STAT5B)
protein.
details
Inferred
Receptor tyrosine-protein kinase erbB-2 -
ERBB2
-  
Homo sapiens
LIG_SH2_III
ERBB2_HUMAN
1131
1147
Binary
Physicochemical compatibility
Phosphorylation of Y1139 in the SH2-binding motif of
Receptor tyrosine-protein kinase erbB-2 (ERBB2)
induces binding to the
Signal transducer and activator of transcription 6 (STAT6)
protein.
details
Inferred
LIG_SH2_III
ERBB2_HUMAN
1131
1147
Binary
Physicochemical compatibility
Phosphorylation of Y1139 in the SH2-binding motif of
Receptor tyrosine-protein kinase erbB-2 (ERBB2)
induces binding to the
Signal transducer and activator of transcription 6 (STAT6)
protein.
details
Inferred
Tyrosine-protein kinase ABL1 -
ABL1
-  
Homo sapiens
LIG_SH2_III
EGFR_HUMAN
1008
1024
Binary
Physicochemical compatibility
Phosphorylation of Y1016 in the SH2-binding motif of
Epidermal growth factor receptor (EGFR)
induces binding to the
Signal transducer and activator of transcription 6 (STAT6)
protein.
details
Inferred
Tyrosine-protein kinase JAK1 -
JAK1
-  
Homo sapiens
LIG_SH2_III
INGR1_HUMAN
457
461
Binary
Physicochemical compatibility
Phosphorylation of Y457 in the SH2-binding motif of
Interferon gamma receptor 1 (IFNGR1)
induces binding to the
Signal transducer and activator of transcription 1-alpha/beta (STAT1)
protein.
details
Inferred
Tyrosine-protein kinase JAK2 -
JAK2
-  
Homo sapiens
LIG_SH2_III
EPOR_HUMAN
360
376
Binary
Physicochemical compatibility
Phosphorylation of Y368 in the SH2-binding motif of
Erythropoietin receptor (EPOR)
induces binding to the
Signal transducer and activator of transcription 5B (STAT5B)
protein.
details
Inferred
LIG_SH2_III
JAK2_MOUSE
804
820
Binary
Physicochemical compatibility
Phosphorylation of Y813 in the SH2-binding motif of
Tyrosine-protein kinase JAK2 (Jak2)
induces binding to the
Signal transducer and activator of transcription 5B (Stat5b)
protein.
details
Inferred
LIG_SH2_III
STA5A_HUMAN
686
702
Binary
Physicochemical compatibility
Phosphorylation of Y694 in the SH2-binding motif of
Signal transducer and activator of transcription 5A (STAT5A)
induces binding to the
Signal transducer and activator of transcription 5B (STAT5B)
protein.
details
Inferred
LIG_SH2_III
STA5A_HUMAN
686
702
Binary
Physicochemical compatibility
Phosphorylation of Y694 in the SH2-binding motif of
Signal transducer and activator of transcription 5A (STAT5A)
induces binding to the
Signal transducer and activator of transcription 5B (STAT5B)
protein.
details
Inferred
Tyrosine-protein kinase JAK2 -
JAK2
-  
Mus musculus
LIG_SH2_III
JAK2_MOUSE
804
820
Binary
Physicochemical compatibility
Phosphorylation of Y813 in the SH2-binding motif of
Tyrosine-protein kinase JAK2 (Jak2)
induces binding to the
Signal transducer and activator of transcription 5B (Stat5b)
protein.
details
Inferred
Tyrosine-protein kinase JAK3 -
JAK3
-  
Homo sapiens
LIG_SH2_III
STA5A_HUMAN
686
702
Binary
Physicochemical compatibility
Phosphorylation of Y694 in the SH2-binding motif of
Signal transducer and activator of transcription 5A (STAT5A)
induces binding to the
Signal transducer and activator of transcription 5B (STAT5B)
protein.
details
Inferred
Tyrosine-protein kinase Lck -
LCK
-  
Homo sapiens
LIG_SH2_III
IL2RB_HUMAN
531
540
Binary
Physicochemical compatibility
Phosphorylation of Y536 in the SH2-binding motif of
Interleukin-2 receptor subunit beta (IL2RB)
induces binding to the
Signal transducer and activator of transcription 5A (STAT5A)
protein.
details
Inferred
LIG_SH2_III
IL2RB_HUMAN
531
540
Binary
Physicochemical compatibility
Phosphorylation of Y536 in the SH2-binding motif of
Interleukin-2 receptor subunit beta (IL2RB)
induces binding to the
Signal transducer and activator of transcription 5A (STAT5A)
protein.
details
Inferred
LIG_SH2_III
IL2RB_HUMAN
528
544
Binary
Physicochemical compatibility
Phosphorylation of Y536 in the SH2-binding motif of
Interleukin-2 receptor subunit beta (IL2RB)
induces binding to the
Signal transducer and activator of transcription 5B (STAT5B)
protein.
details
Inferred
LIG_SH2_III
IL2RB_HUMAN
528
544
Binary
Physicochemical compatibility
Phosphorylation of Y536 in the SH2-binding motif of
Interleukin-2 receptor subunit beta (IL2RB)
induces binding to the
Signal transducer and activator of transcription 5B (STAT5B)
protein.
details
Inferred
LIG_SH2_III
STA5A_HUMAN
686
702
Binary
Physicochemical compatibility
Phosphorylation of Y694 in the SH2-binding motif of
Signal transducer and activator of transcription 5A (STAT5A)
induces binding to the
Signal transducer and activator of transcription 5B (STAT5B)
protein.
details
Inferred
Tyrosine-protein kinase Lyn -
LYN
-  
Homo sapiens
LIG_SH2_III
EPOR_HUMAN
360
376
Binary
Physicochemical compatibility
Phosphorylation of Y368 in the SH2-binding motif of
Erythropoietin receptor (EPOR)
induces binding to the
Signal transducer and activator of transcription 5B (STAT5B)
protein.
details
Inferred
LIG_SH2_III
STA5A_HUMAN
686
702
Binary
Physicochemical compatibility
Phosphorylation of Y694 in the SH2-binding motif of
Signal transducer and activator of transcription 5A (STAT5A)
induces binding to the
Signal transducer and activator of transcription 5B (STAT5B)
protein.
details
Inferred
Tyrosine-protein kinase Lyn -
LYN
-  
Mus musculus
LIG_SH2_III
STA5A_HUMAN
686
702
Binary
Physicochemical compatibility
Phosphorylation of Y694 in the SH2-binding motif of
Signal transducer and activator of transcription 5A (STAT5A)
induces binding to the
Signal transducer and activator of transcription 5B (STAT5B)
protein.
details
Inferred
Tyrosine-protein kinase SYK -
SYK
-  
Homo sapiens
LIG_SH2_III
STA5A_HUMAN
686
702
Binary
Physicochemical compatibility
Phosphorylation of Y694 in the SH2-binding motif of
Signal transducer and activator of transcription 5A (STAT5A)
induces binding to the
Signal transducer and activator of transcription 5B (STAT5B)
protein.
details
Inferred