About Help Definitions Submit Search Analyse Browse Home


Group by :Switch typeMotif classProteinEnzymePathway         Hide inferred   Group Index    Colouring Info              Filtered: UNIPROT:P05412 (33 hits) x
submit


x  Coloured by: Modifier evidence source
          Curated          inferred


x  Index
Casein kinase II subunit alphaCyclin-dependent kinase 3Glycogen synthase kinase-3 alpha
Glycogen synthase kinase-3 betaMitogen-activated protein kinase 15Mitogen-activated protein kinase 8
Mitogen-activated protein kinase 9Serine/threonine-protein kinase D1Serine/threonine-protein kinase PLK3
Serine/threonine-protein kinase VRK1


MotifProteinStartEndSwitch TypeSwitch SubtypeSwitch descriptionInformationEvidence

Casein kinase II subunit alpha - CSNK2A1 -  Homo sapiens
MOD_GSK3_1 JUN_HUMAN236243BinaryPhysicochemical compatibilityPhosphorylation of Transcription factor AP-1 (JUN) at S243 primes the protein for phosphorylation at T239 by Glycogen synthase kinase-3 beta (GSK3B).
details
Inferred
MOD_GSK3_1 JUN_HUMAN236243SpecificityAltered binding specificityTranscription factor AP-1 (JUN) is primed by an unknown kinase for phosphorylation by Glycogen synthase kinase-3 beta (GSK3B), which targets JUN to the SCF ubiquitin ligase complex, F-box/WD repeat-containing protein 7 (FBXW7) that marks JUN for degradation. In v-Jun (Viral jun-transforming protein (JUN)) the residue corresponding to S243 is mutated to phenylalanine, which protects v-Jun (JUN) from degradation.
details
Inferred
DEG_SCF_FBW7_1 JUN_HUMAN236243SpecificityAltered binding specificityTranscription factor AP-1 (JUN) is primed by an unknown kinase for phosphorylation by Glycogen synthase kinase-3 beta (GSK3B), which targets JUN to the SCF ubiquitin ligase complex, F-box/WD repeat-containing protein 7 (FBXW7) that marks JUN for degradation. In v-Jun (Viral jun-transforming protein (JUN)) the residue corresponding to S243 is mutated to phenylalanine, which protects v-Jun (JUN) from degradation.
details
Inferred

Cyclin-dependent kinase 3 - CDK3 -  Homo sapiens
DOC_WW_Pin1_4 JUN_HUMAN6065BinaryPhysicochemical compatibilityPhosphorylation of S63 in the Pin1-binding motif of Transcription factor AP-1 (JUN) induces binding to the Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 (PIN1) protein.
details
Inferred
DOC_WW_Pin1_4 JUN_HUMAN7075BinaryPhysicochemical compatibilityPhosphorylation of S73 in the Pin1-binding motif of Transcription factor AP-1 (JUN) induces binding to the Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 (PIN1) protein.
details
Inferred

Glycogen synthase kinase-3 alpha - GSK3A -  Homo sapiens
MOD_GSK3_1 JUN_HUMAN236243BinaryPhysicochemical compatibilityPhosphorylation of Transcription factor AP-1 (JUN) at S243 primes the protein for phosphorylation at T239 by Glycogen synthase kinase-3 beta (GSK3B).
details
Inferred
MOD_GSK3_1 JUN_HUMAN236243SpecificityAltered binding specificityTranscription factor AP-1 (JUN) is primed by an unknown kinase for phosphorylation by Glycogen synthase kinase-3 beta (GSK3B), which targets JUN to the SCF ubiquitin ligase complex, F-box/WD repeat-containing protein 7 (FBXW7) that marks JUN for degradation. In v-Jun (Viral jun-transforming protein (JUN)) the residue corresponding to S243 is mutated to phenylalanine, which protects v-Jun (JUN) from degradation.
details
Inferred
MOD_GSK3_1 JUN_HUMAN236243SpecificityAltered binding specificityTranscription factor AP-1 (JUN) is primed by an unknown kinase for phosphorylation by Glycogen synthase kinase-3 beta (GSK3B), which targets JUN to the SCF ubiquitin ligase complex, F-box/WD repeat-containing protein 7 (FBXW7) that marks JUN for degradation. In v-Jun (Viral jun-transforming protein (JUN)) the residue corresponding to S243 is mutated to phenylalanine, which protects v-Jun (JUN) from degradation.
details
Inferred
MOD_GSK3_1 JUN_HUMAN236243SpecificityAltered binding specificityTranscription factor AP-1 (JUN) is primed by an unknown kinase for phosphorylation by Glycogen synthase kinase-3 beta (GSK3B), which targets JUN to the SCF ubiquitin ligase complex, F-box/WD repeat-containing protein 7 (FBXW7) that marks JUN for degradation. In v-Jun (Viral jun-transforming protein (JUN)) the residue corresponding to S243 is mutated to phenylalanine, which protects v-Jun (JUN) from degradation.
details
Inferred
DEG_SCF_FBW7_1 JUN_HUMAN236243SpecificityAltered binding specificityTranscription factor AP-1 (JUN) is primed by an unknown kinase for phosphorylation by Glycogen synthase kinase-3 beta (GSK3B), which targets JUN to the SCF ubiquitin ligase complex, F-box/WD repeat-containing protein 7 (FBXW7) that marks JUN for degradation. In v-Jun (Viral jun-transforming protein (JUN)) the residue corresponding to S243 is mutated to phenylalanine, which protects v-Jun (JUN) from degradation.
details
Inferred
DEG_SCF_FBW7_1 JUN_HUMAN236243SpecificityAltered binding specificityTranscription factor AP-1 (JUN) is primed by an unknown kinase for phosphorylation by Glycogen synthase kinase-3 beta (GSK3B), which targets JUN to the SCF ubiquitin ligase complex, F-box/WD repeat-containing protein 7 (FBXW7) that marks JUN for degradation. In v-Jun (Viral jun-transforming protein (JUN)) the residue corresponding to S243 is mutated to phenylalanine, which protects v-Jun (JUN) from degradation.
details
Inferred
DEG_SCF_FBW7_1 JUN_HUMAN236243SpecificityAltered binding specificityTranscription factor AP-1 (JUN) is primed by an unknown kinase for phosphorylation by Glycogen synthase kinase-3 beta (GSK3B), which targets JUN to the SCF ubiquitin ligase complex, F-box/WD repeat-containing protein 7 (FBXW7) that marks JUN for degradation. In v-Jun (Viral jun-transforming protein (JUN)) the residue corresponding to S243 is mutated to phenylalanine, which protects v-Jun (JUN) from degradation.
details
Inferred

Glycogen synthase kinase-3 beta - GSK3B -  Homo sapiens
MOD_GSK3_1 JUN_HUMAN236243BinaryPhysicochemical compatibilityPhosphorylation of Transcription factor AP-1 (JUN) at S243 primes the protein for phosphorylation at T239 by Glycogen synthase kinase-3 beta (GSK3B).
details
Inferred
MOD_GSK3_1 JUN_HUMAN236243SpecificityAltered binding specificityTranscription factor AP-1 (JUN) is primed by an unknown kinase for phosphorylation by Glycogen synthase kinase-3 beta (GSK3B), which targets JUN to the SCF ubiquitin ligase complex, F-box/WD repeat-containing protein 7 (FBXW7) that marks JUN for degradation. In v-Jun (Viral jun-transforming protein (JUN)) the residue corresponding to S243 is mutated to phenylalanine, which protects v-Jun (JUN) from degradation.
details
Inferred
MOD_GSK3_1 JUN_HUMAN236243SpecificityAltered binding specificityTranscription factor AP-1 (JUN) is primed by an unknown kinase for phosphorylation by Glycogen synthase kinase-3 beta (GSK3B), which targets JUN to the SCF ubiquitin ligase complex, F-box/WD repeat-containing protein 7 (FBXW7) that marks JUN for degradation. In v-Jun (Viral jun-transforming protein (JUN)) the residue corresponding to S243 is mutated to phenylalanine, which protects v-Jun (JUN) from degradation.
details
Inferred
DEG_SCF_FBW7_1 JUN_HUMAN236243SpecificityAltered binding specificityTranscription factor AP-1 (JUN) is primed by an unknown kinase for phosphorylation by Glycogen synthase kinase-3 beta (GSK3B), which targets JUN to the SCF ubiquitin ligase complex, F-box/WD repeat-containing protein 7 (FBXW7) that marks JUN for degradation. In v-Jun (Viral jun-transforming protein (JUN)) the residue corresponding to S243 is mutated to phenylalanine, which protects v-Jun (JUN) from degradation.
details
Curated

Mitogen-activated protein kinase 15 - MAPK15 -  Homo sapiens
DOC_WW_Pin1_4 JUN_HUMAN6065BinaryPhysicochemical compatibilityPhosphorylation of S63 in the Pin1-binding motif of Transcription factor AP-1 (JUN) induces binding to the Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 (PIN1) protein.
details
Inferred
DOC_WW_Pin1_4 JUN_HUMAN7075BinaryPhysicochemical compatibilityPhosphorylation of S73 in the Pin1-binding motif of Transcription factor AP-1 (JUN) induces binding to the Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 (PIN1) protein.
details
Inferred

Mitogen-activated protein kinase 8 - MAPK8 -  Homo sapiens
DOC_WW_Pin1_4 JUN_HUMAN6065BinaryPhysicochemical compatibilityPhosphorylation of S63 in the Pin1-binding motif of Transcription factor AP-1 (JUN) induces binding to the Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 (PIN1) protein.
details
Inferred
DOC_WW_Pin1_4 JUN_HUMAN6065BinaryPhysicochemical compatibilityPhosphorylation of S63 in the Pin1-binding motif of Transcription factor AP-1 (JUN) induces binding to the Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 (PIN1) protein.
details
Inferred
DOC_WW_Pin1_4 JUN_HUMAN6065BinaryPhysicochemical compatibilityPhosphorylation of S63 in the Pin1-binding motif of Transcription factor AP-1 (JUN) induces binding to the Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 (PIN1) protein.
details
Inferred
DOC_WW_Pin1_4 JUN_HUMAN7075BinaryPhysicochemical compatibilityPhosphorylation of S73 in the Pin1-binding motif of Transcription factor AP-1 (JUN) induces binding to the Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 (PIN1) protein.
details
Inferred
DOC_WW_Pin1_4 JUN_HUMAN7075BinaryPhysicochemical compatibilityPhosphorylation of S73 in the Pin1-binding motif of Transcription factor AP-1 (JUN) induces binding to the Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 (PIN1) protein.
details
Inferred

Mitogen-activated protein kinase 9 - MAPK9 -  Homo sapiens
DOC_WW_Pin1_4 JUN_HUMAN6065BinaryPhysicochemical compatibilityPhosphorylation of S63 in the Pin1-binding motif of Transcription factor AP-1 (JUN) induces binding to the Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 (PIN1) protein.
details
Inferred
DOC_WW_Pin1_4 JUN_HUMAN6065BinaryPhysicochemical compatibilityPhosphorylation of S63 in the Pin1-binding motif of Transcription factor AP-1 (JUN) induces binding to the Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 (PIN1) protein.
details
Inferred
DOC_WW_Pin1_4 JUN_HUMAN7075BinaryPhysicochemical compatibilityPhosphorylation of S73 in the Pin1-binding motif of Transcription factor AP-1 (JUN) induces binding to the Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 (PIN1) protein.
details
Inferred

Serine/threonine-protein kinase D1 - PRKD1 -  Homo sapiens
DOC_WW_Pin1_4 JUN_HUMAN6065BinaryPhysicochemical compatibilityPhosphorylation of S63 in the Pin1-binding motif of Transcription factor AP-1 (JUN) induces binding to the Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 (PIN1) protein.
details
Inferred

Serine/threonine-protein kinase PLK3 - PLK3 -  Homo sapiens
DOC_WW_Pin1_4 JUN_HUMAN6065BinaryPhysicochemical compatibilityPhosphorylation of S63 in the Pin1-binding motif of Transcription factor AP-1 (JUN) induces binding to the Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 (PIN1) protein.
details
Inferred
DOC_WW_Pin1_4 JUN_HUMAN7075BinaryPhysicochemical compatibilityPhosphorylation of S73 in the Pin1-binding motif of Transcription factor AP-1 (JUN) induces binding to the Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 (PIN1) protein.
details
Inferred

Serine/threonine-protein kinase VRK1 - VRK1 -  Homo sapiens
DOC_WW_Pin1_4 JUN_HUMAN6065BinaryPhysicochemical compatibilityPhosphorylation of S63 in the Pin1-binding motif of Transcription factor AP-1 (JUN) induces binding to the Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 (PIN1) protein.
details
Inferred
DOC_WW_Pin1_4 JUN_HUMAN6065BinaryPhysicochemical compatibilityPhosphorylation of S63 in the Pin1-binding motif of Transcription factor AP-1 (JUN) induces binding to the Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 (PIN1) protein.
details
Inferred
DOC_WW_Pin1_4 JUN_HUMAN7075BinaryPhysicochemical compatibilityPhosphorylation of S73 in the Pin1-binding motif of Transcription factor AP-1 (JUN) induces binding to the Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 (PIN1) protein.
details
Inferred
DOC_WW_Pin1_4 JUN_HUMAN7075BinaryPhysicochemical compatibilityPhosphorylation of S73 in the Pin1-binding motif of Transcription factor AP-1 (JUN) induces binding to the Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 (PIN1) protein.
details
Inferred
           
Please send any suggestions/comments to: switches@elm.eu.org