switches.ELM

Group by :Switch type Motif class Protein Enzyme Pathway Hide inferred Group Index Colouring Info Filtered: UNIPROT:P43405 (34 hits) x

x Coloured by: Modifier evidence source
Curated inferred

x Index

Tyrosine-protein kinase Blk	Tyrosine-protein kinase Fyn	Tyrosine-protein kinase Fyn (Mus)
Tyrosine-protein kinase Lyn	Tyrosine-protein kinase Lyn (Mus)	Tyrosine-protein kinase SYK

Motif

Protein

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End

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Information

Evidence

Tyrosine-protein kinase Blk - BLK - Homo sapiens
LIG_TYR_ITAM	FCG2A_HUMAN	285	307	Avidity‑sensing	Phosphorylation of Y288 and Y304 in the ITAM motif of Low affinity immunoglobulin gamma Fc region receptor II-a (FCGR2A) induces high-avidity binding to the tandem SH2 domains of Tyrosine-protein kinase SYK (SYK).	details	Inferred
LIG_TYR_ITAM	FCG2A_HUMAN	285	307	Avidity‑sensing	Phosphorylation of Y288 and Y304 in the ITAM motif of Low affinity immunoglobulin gamma Fc region receptor II-a (FCGR2A) induces high-avidity binding to the tandem SH2 domains of Tyrosine-protein kinase SYK (SYK).	details	Inferred
LIG_TYR_ITAM	FCG2A_HUMAN	285	307	Avidity‑sensing	Phosphorylation of Y288 and Y304 in the ITAM motif of Low affinity immunoglobulin gamma Fc region receptor II-a (FCGR2A) induces high-avidity binding to the tandem SH2 domains of Tyrosine-protein kinase SYK (SYK).	details	Inferred
LIG_TYR_ITAM	FCG2A_HUMAN	285	307	Avidity‑sensing	Phosphorylation of Y288 and Y304 in the ITAM motif of Low affinity immunoglobulin gamma Fc region receptor II-a (FCGR2A) induces high-avidity binding to the tandem SH2 domains of Tyrosine-protein kinase SYK (SYK).	details	Inferred
LIG_TYR_ITAM	FCG2A_HUMAN	285	307	Avidity‑sensing	Phosphorylation of Y288 and Y304 in the ITAM motif of Low affinity immunoglobulin gamma Fc region receptor II-a (FCGR2A) induces high-avidity binding to the tandem SH2 domains of Tyrosine-protein kinase SYK (SYK).	details	Inferred
LIG_TYR_ITAM	FCG2A_HUMAN	285	307	Avidity‑sensing	Phosphorylation of Y288 and Y304 in the ITAM motif of Low affinity immunoglobulin gamma Fc region receptor II-a (FCGR2A) induces high-avidity binding to the tandem SH2 domains of Tyrosine-protein kinase SYK (SYK).	details	Inferred
LIG_TYR_ITAM	FCG2A_HUMAN	285	307	Avidity‑sensing	Phosphorylation of Y288 and Y304 in the ITAM motif of Low affinity immunoglobulin gamma Fc region receptor II-a (FCGR2A) induces high-avidity binding to the tandem SH2 domains of Tyrosine-protein kinase SYK (SYK).	details	Inferred
LIG_TYR_ITAM	FCG2A_HUMAN	285	307	Avidity‑sensing	Phosphorylation of Y288 and Y304 in the ITAM motif of Low affinity immunoglobulin gamma Fc region receptor II-a (FCGR2A) induces high-avidity binding to the tandem SH2 domains of Tyrosine-protein kinase SYK (SYK).	details	Inferred
Tyrosine-protein kinase Fyn - FYN - Homo sapiens
LIG_TYR_ITAM	CD3E_HUMAN	185	202	Avidity‑sensing	Phosphorylation of Y188 and Y199 in the ITAM motif of T-cell surface glycoprotein CD3 epsilon chain (CD3E) induces high-avidity binding to the tandem SH2 domains of Tyrosine-protein kinase SYK (SYK).	details	Inferred
LIG_TYR_ITAM	CD3E_HUMAN	185	202	Avidity‑sensing	Phosphorylation of Y188 and Y199 in the ITAM motif of T-cell surface glycoprotein CD3 epsilon chain (CD3E) induces high-avidity binding to the tandem SH2 domains of Tyrosine-protein kinase SYK (SYK).	details	Inferred
LIG_TYR_ITAM	CD3E_HUMAN	185	202	Avidity‑sensing	Phosphorylation of Y188 and Y199 in the ITAM motif of T-cell surface glycoprotein CD3 epsilon chain (CD3E) induces high-avidity binding to the tandem SH2 domains of Tyrosine-protein kinase SYK (SYK).	details	Inferred
LIG_TYR_ITAM	CD3E_HUMAN	185	202	Avidity‑sensing	Phosphorylation of Y188 and Y199 in the ITAM motif of T-cell surface glycoprotein CD3 epsilon chain (CD3E) induces high-avidity binding to the tandem SH2 domains of Tyrosine-protein kinase SYK (SYK).	details	Inferred
LIG_TYR_ITAM	FCG2A_HUMAN	285	307	Avidity‑sensing	Phosphorylation of Y288 and Y304 in the ITAM motif of Low affinity immunoglobulin gamma Fc region receptor II-a (FCGR2A) induces high-avidity binding to the tandem SH2 domains of Tyrosine-protein kinase SYK (SYK).	details	Inferred
LIG_TYR_ITAM	FCG2A_HUMAN	285	307	Avidity‑sensing	Phosphorylation of Y288 and Y304 in the ITAM motif of Low affinity immunoglobulin gamma Fc region receptor II-a (FCGR2A) induces high-avidity binding to the tandem SH2 domains of Tyrosine-protein kinase SYK (SYK).	details	Inferred
LIG_TYR_ITAM	FCG2A_HUMAN	285	307	Avidity‑sensing	Phosphorylation of Y288 and Y304 in the ITAM motif of Low affinity immunoglobulin gamma Fc region receptor II-a (FCGR2A) induces high-avidity binding to the tandem SH2 domains of Tyrosine-protein kinase SYK (SYK).	details	Inferred
LIG_TYR_ITAM	FCG2A_HUMAN	285	307	Avidity‑sensing	Phosphorylation of Y288 and Y304 in the ITAM motif of Low affinity immunoglobulin gamma Fc region receptor II-a (FCGR2A) induces high-avidity binding to the tandem SH2 domains of Tyrosine-protein kinase SYK (SYK).	details	Inferred
LIG_TYR_ITAM	FCG2A_HUMAN	285	307	Avidity‑sensing	Phosphorylation of Y288 and Y304 in the ITAM motif of Low affinity immunoglobulin gamma Fc region receptor II-a (FCGR2A) induces high-avidity binding to the tandem SH2 domains of Tyrosine-protein kinase SYK (SYK).	details	Inferred
LIG_TYR_ITAM	FCG2A_HUMAN	285	307	Avidity‑sensing	Phosphorylation of Y288 and Y304 in the ITAM motif of Low affinity immunoglobulin gamma Fc region receptor II-a (FCGR2A) induces high-avidity binding to the tandem SH2 domains of Tyrosine-protein kinase SYK (SYK).	details	Inferred
Tyrosine-protein kinase Fyn - FYN - Mus musculus
LIG_TYR_ITAM	FCG2A_HUMAN	285	307	Avidity‑sensing	Phosphorylation of Y288 and Y304 in the ITAM motif of Low affinity immunoglobulin gamma Fc region receptor II-a (FCGR2A) induces high-avidity binding to the tandem SH2 domains of Tyrosine-protein kinase SYK (SYK).	details	Inferred
LIG_TYR_ITAM	FCG2A_HUMAN	285	307	Avidity‑sensing	Phosphorylation of Y288 and Y304 in the ITAM motif of Low affinity immunoglobulin gamma Fc region receptor II-a (FCGR2A) induces high-avidity binding to the tandem SH2 domains of Tyrosine-protein kinase SYK (SYK).	details	Inferred
Tyrosine-protein kinase Lyn - LYN - Homo sapiens
LIG_TYR_ITAM	FCG2A_HUMAN	285	307	Avidity‑sensing	Phosphorylation of Y288 and Y304 in the ITAM motif of Low affinity immunoglobulin gamma Fc region receptor II-a (FCGR2A) induces high-avidity binding to the tandem SH2 domains of Tyrosine-protein kinase SYK (SYK).	details	Inferred
LIG_TYR_ITAM	FCG2A_HUMAN	285	307	Avidity‑sensing	Phosphorylation of Y288 and Y304 in the ITAM motif of Low affinity immunoglobulin gamma Fc region receptor II-a (FCGR2A) induces high-avidity binding to the tandem SH2 domains of Tyrosine-protein kinase SYK (SYK).	details	Inferred
LIG_TYR_ITAM	FCG2A_HUMAN	285	307	Avidity‑sensing	Phosphorylation of Y288 and Y304 in the ITAM motif of Low affinity immunoglobulin gamma Fc region receptor II-a (FCGR2A) induces high-avidity binding to the tandem SH2 domains of Tyrosine-protein kinase SYK (SYK).	details	Inferred
LIG_TYR_ITAM	FCG2A_HUMAN	285	307	Avidity‑sensing	Phosphorylation of Y288 and Y304 in the ITAM motif of Low affinity immunoglobulin gamma Fc region receptor II-a (FCGR2A) induces high-avidity binding to the tandem SH2 domains of Tyrosine-protein kinase SYK (SYK).	details	Inferred
LIG_TYR_ITAM	FCG2A_HUMAN	285	307	Avidity‑sensing	Phosphorylation of Y288 and Y304 in the ITAM motif of Low affinity immunoglobulin gamma Fc region receptor II-a (FCGR2A) induces high-avidity binding to the tandem SH2 domains of Tyrosine-protein kinase SYK (SYK).	details	Inferred
LIG_TYR_ITAM	FCG2A_HUMAN	285	307	Avidity‑sensing	Phosphorylation of Y288 and Y304 in the ITAM motif of Low affinity immunoglobulin gamma Fc region receptor II-a (FCGR2A) induces high-avidity binding to the tandem SH2 domains of Tyrosine-protein kinase SYK (SYK).	details	Inferred
Tyrosine-protein kinase Lyn - LYN - Mus musculus
LIG_TYR_ITAM	FCG2A_HUMAN	285	307	Avidity‑sensing	Phosphorylation of Y288 and Y304 in the ITAM motif of Low affinity immunoglobulin gamma Fc region receptor II-a (FCGR2A) induces high-avidity binding to the tandem SH2 domains of Tyrosine-protein kinase SYK (SYK).	details	Inferred
LIG_TYR_ITAM	FCG2A_HUMAN	285	307	Avidity‑sensing	Phosphorylation of Y288 and Y304 in the ITAM motif of Low affinity immunoglobulin gamma Fc region receptor II-a (FCGR2A) induces high-avidity binding to the tandem SH2 domains of Tyrosine-protein kinase SYK (SYK).	details	Inferred
Tyrosine-protein kinase SYK - SYK - Homo sapiens
LIG_TYR_ITAM	FCG2A_HUMAN	285	307	Avidity‑sensing	Phosphorylation of Y288 and Y304 in the ITAM motif of Low affinity immunoglobulin gamma Fc region receptor II-a (FCGR2A) induces high-avidity binding to the tandem SH2 domains of Tyrosine-protein kinase SYK (SYK).	details	Inferred
LIG_TYR_ITAM	FCG2A_HUMAN	285	307	Avidity‑sensing	Phosphorylation of Y288 and Y304 in the ITAM motif of Low affinity immunoglobulin gamma Fc region receptor II-a (FCGR2A) induces high-avidity binding to the tandem SH2 domains of Tyrosine-protein kinase SYK (SYK).	details	Inferred
LIG_TYR_ITAM	FCG2A_HUMAN	285	307	Avidity‑sensing	Phosphorylation of Y288 and Y304 in the ITAM motif of Low affinity immunoglobulin gamma Fc region receptor II-a (FCGR2A) induces high-avidity binding to the tandem SH2 domains of Tyrosine-protein kinase SYK (SYK).	details	Inferred
LIG_TYR_ITAM	FCG2A_HUMAN	285	307	Avidity‑sensing	Phosphorylation of Y288 and Y304 in the ITAM motif of Low affinity immunoglobulin gamma Fc region receptor II-a (FCGR2A) induces high-avidity binding to the tandem SH2 domains of Tyrosine-protein kinase SYK (SYK).	details	Inferred
LIG_TYR_ITAM	FCG2A_HUMAN	285	307	Avidity‑sensing	Phosphorylation of Y288 and Y304 in the ITAM motif of Low affinity immunoglobulin gamma Fc region receptor II-a (FCGR2A) induces high-avidity binding to the tandem SH2 domains of Tyrosine-protein kinase SYK (SYK).	details	Inferred
LIG_TYR_ITAM	FCG2A_HUMAN	285	307	Avidity‑sensing	Phosphorylation of Y288 and Y304 in the ITAM motif of Low affinity immunoglobulin gamma Fc region receptor II-a (FCGR2A) induces high-avidity binding to the tandem SH2 domains of Tyrosine-protein kinase SYK (SYK).	details	Inferred