switches.ELM

Group by :Switch type Motif class Protein Enzyme Pathway Hide inferred Group Index Colouring Info Filtered: UNIPROT:Q05397 (11 hits) x

x Coloured by: Modifier evidence source
Curated inferred

x Index

Cyclin-dependent kinase 5	Focal adhesion kinase 1	Hepatocyte growth factor receptor
Proto-oncogene tyrosine-protein kinase Src	Tyrosine-protein kinase Fgr

Motif

Protein

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Information

Evidence

Cyclin-dependent kinase 5 - CDK5 - Homo sapiens
DOC_WW_Pin1_4	FAK1_HUMAN	907	912	Binary	Physicochemical compatibility	Phosphorylation of S910 in the Pin1-binding motif of Focal adhesion kinase 1 (PTK2) induces binding to the Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 (PIN1) protein.	details	Inferred
Focal adhesion kinase 1 - PTK2 - Homo sapiens
LIG_SH2_IA	FAK1_HUMAN	389	405	Binary	Physicochemical compatibility	Phosphorylation of Y397 in the SH2-binding motif of Focal adhesion kinase 1 (PTK2) induces binding to the Cytoplasmic protein NCK2 (NCK2) protein.	details	Inferred
LIG_SH2_IA	FAK1_HUMAN	389	405	Binary	Physicochemical compatibility	Phosphorylation of Y397 in the SH2-binding motif of Focal adhesion kinase 1 (PTK2) induces binding to the Cytoplasmic protein NCK2 (NCK2) protein.	details	Inferred
LIG_SH2_SRC	FAK1_HUMAN	397	400	Binary	Physicochemical compatibility	Phosphorylation of Y397 in the SH2-binding motif of Focal adhesion kinase 1 (PTK2) induces binding to Neuronal proto-oncogene tyrosine-protein kinase Src (Src).	details	Inferred
LIG_SH2_SRC	FAK1_HUMAN	397	400	Binary	Physicochemical compatibility	Phosphorylation of Y397 in the SH2-binding motif of Focal adhesion kinase 1 (PTK2) induces binding to Neuronal proto-oncogene tyrosine-protein kinase Src (Src).	details	Inferred
Hepatocyte growth factor receptor - MET - Homo sapiens
LIG_SH2_IA	FAK1_HUMAN	389	405	Binary	Physicochemical compatibility	Phosphorylation of Y397 in the SH2-binding motif of Focal adhesion kinase 1 (PTK2) induces binding to the Cytoplasmic protein NCK2 (NCK2) protein.	details	Inferred
LIG_SH2_SRC	FAK1_HUMAN	397	400	Binary	Physicochemical compatibility	Phosphorylation of Y397 in the SH2-binding motif of Focal adhesion kinase 1 (PTK2) induces binding to Neuronal proto-oncogene tyrosine-protein kinase Src (Src).	details	Inferred
Proto-oncogene tyrosine-protein kinase Src - SRC - Homo sapiens
LIG_SH2_IA	FAK1_HUMAN	389	405	Binary	Physicochemical compatibility	Phosphorylation of Y397 in the SH2-binding motif of Focal adhesion kinase 1 (PTK2) induces binding to the Cytoplasmic protein NCK2 (NCK2) protein.	details	Inferred
LIG_SH2_SRC	FAK1_HUMAN	397	400	Binary	Physicochemical compatibility	Phosphorylation of Y397 in the SH2-binding motif of Focal adhesion kinase 1 (PTK2) induces binding to Neuronal proto-oncogene tyrosine-protein kinase Src (Src).	details	Inferred
Tyrosine-protein kinase Fgr - FGR - Homo sapiens
LIG_SH2_IA	FAK1_HUMAN	389	405	Binary	Physicochemical compatibility	Phosphorylation of Y397 in the SH2-binding motif of Focal adhesion kinase 1 (PTK2) induces binding to the Cytoplasmic protein NCK2 (NCK2) protein.	details	Inferred
LIG_SH2_SRC	FAK1_HUMAN	397	400	Binary	Physicochemical compatibility	Phosphorylation of Y397 in the SH2-binding motif of Focal adhesion kinase 1 (PTK2) induces binding to Neuronal proto-oncogene tyrosine-protein kinase Src (Src).	details	Inferred