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Group by :Switch typeMotif classProteinEnzymePathway            Group Index    Colouring Info              Filtered: UNIPROT:P16333 (4 hits) x
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  Domain hiding  Altered binding specificity  Motif hiding  Composite binding site formation
  Uncategorised  Rheostatic  Allostery  Avidity-sensing
  Physicochemical compatibility  Pre-translational  Competition

x  Index
LIG_SH2_IALIG_SH2_SRCLIG_SH3_2


ProteinStartEndSwitch TypeSwitch SubtypeSwitch DescriptionInformation

LIG_SH2_IA -
EPHA3_HUMAN597606BinaryPhysicochemical compatibilityPhosphorylation of Y602 in the SH2-binding motif of Ephrin type-A receptor 3 (EPHA3) induces binding to the Cytoplasmic protein NCK1 (NCK1) protein.
details
DCD_HUMAN1525BinaryPhysicochemical compatibilityPhosphorylation of Y20 in the SH2-binding motif of Dermcidin (DCD) induces binding to the Cytoplasmic protein NCK1 (NCK1) protein.
details

LIG_SH2_SRC - Src-family Src Homology 2 (SH2) domains binding motif.
EGFR_HUMAN10161019BinaryPhysicochemical compatibilityPhosphorylation of Y1016 in the SH2-binding motif of Epidermal growth factor receptor (EGFR) induces binding to Cytoplasmic protein NCK1 (NCK1).
details

LIG_SH3_2 - This is the motif recognized by class II SH3 domains
PAK1_HUMAN1318BinaryPhysicochemical compatibilityPhosphorylation of S21 adjacent to the SH3-binding motif of Serine/threonine-protein kinase PAK 1 (PAK1) by RAC subfamily inhibits binding to Cytoplasmic protein NCK1 (NCK1), which regulates its localization to focal contacts.
details
           
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