switches.ELM

Group by :Switch type Motif class Protein Enzyme Pathway Hide inferred Group Index Colouring Info Filtered: ELM:LIG_Filamin_2 (2 hits) x

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Curated inferred

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Evidence

Focal adhesion (KEGG - hsa04510)
LIG_Filamin_2	ITB1_HUMAN	783	791	Binary	Pre‑translational	Alternative splicing strongly inhibits the binding of the filamin-binding motif of Integrin beta-1 (ITGB1) to Filamin-A (FLNA), primarily due to the alteration of A to P it seems.	details	Inferred
LIG_Filamin_2	ITB1_HUMAN	783	791	Binary	Pre‑translational	Alternative splicing strongly inhibits the binding of the filamin-binding motif of Integrin beta-1 (ITGB1) to Filamin-B (FLNB), primarily due to the alteration of A to P it seems. Splicing of FLNB also affects this interaction.	details	Inferred