Motif | Protein | Start | End | Switch Type | Switch Subtype | Switch description | Information | Evidence |
Axon guidance (KEGG - hsa04360) | ||||||||
LIG_SH3_2 | PAK1_HUMAN | 13 | 18 | Binary | Physicochemical compatibility | Phosphorylation of S21 adjacent to the SH3-binding motif of Serine/threonine-protein kinase PAK 1 (PAK1) by RAC subfamily inhibits binding to Cytoplasmic protein NCK1 (NCK1), which regulates its localization to focal contacts. | Inferred | |
ErbB signaling pathway (KEGG - hsa04012) | ||||||||
LIG_SH3_2 | PAK1_HUMAN | 13 | 18 | Binary | Physicochemical compatibility | Phosphorylation of S21 adjacent to the SH3-binding motif of Serine/threonine-protein kinase PAK 1 (PAK1) by RAC subfamily inhibits binding to Cytoplasmic protein NCK1 (NCK1), which regulates its localization to focal contacts. | Inferred | |
T cell receptor signaling pathway (KEGG - hsa04660) | ||||||||
LIG_SH3_2 | PAK1_HUMAN | 13 | 18 | Binary | Physicochemical compatibility | Phosphorylation of S21 adjacent to the SH3-binding motif of Serine/threonine-protein kinase PAK 1 (PAK1) by RAC subfamily inhibits binding to Cytoplasmic protein NCK1 (NCK1), which regulates its localization to focal contacts. | Inferred |