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Group by :Switch typeMotif classProteinEnzymePathway         Hide inferred   Group Index    Colouring Info              Filtered: UNIPROT:P19174 (7 hits) x


x  Coloured by: Pathway evidence source
          Curated          inferred


x  Index
Calcium signaling pathwayDAP12 interactionsErbB signaling pathway
NF-kappa B signaling pathwayNatural killer cell mediated cytotoxicityT cell receptor signaling pathway
TCR signaling


MotifProteinStartEndSwitch TypeSwitch SubtypeSwitch descriptionInformationEvidence

Calcium signaling pathway (KEGG - hsa04020)
LIG_SH2_SRC EGFR_HUMAN10161019BinaryPhysicochemical compatibilityPhosphorylation of Y1016 in the SH2-binding motif of Epidermal growth factor receptor (EGFR) induces binding to 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma-1 (PLCG1).
details
Curated

DAP12 interactions (Reactome - 2172127)
LIG_SH2_STAT5 LAT_HUMAN161164BinaryPhysicochemical compatibilityPhosphorylation of Y161 in the SH2-binding motif of Linker for activation of T-cells family member 1 (LAT) induces binding to the 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma-1 (PLCG1) protein.
details
Curated

ErbB signaling pathway (KEGG - hsa04012)
LIG_SH2_SRC EGFR_HUMAN10161019BinaryPhysicochemical compatibilityPhosphorylation of Y1016 in the SH2-binding motif of Epidermal growth factor receptor (EGFR) induces binding to 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma-1 (PLCG1).
details
Curated

NF-kappa B signaling pathway (KEGG - hsa04064)
LIG_SH2_STAT5 LAT_HUMAN161164BinaryPhysicochemical compatibilityPhosphorylation of Y161 in the SH2-binding motif of Linker for activation of T-cells family member 1 (LAT) induces binding to the 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma-1 (PLCG1) protein.
details
Curated

Natural killer cell mediated cytotoxicity (KEGG - hsa04650)
LIG_SH2_STAT5 LAT_HUMAN161164BinaryPhysicochemical compatibilityPhosphorylation of Y161 in the SH2-binding motif of Linker for activation of T-cells family member 1 (LAT) induces binding to the 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma-1 (PLCG1) protein.
details
Curated

T cell receptor signaling pathway (KEGG - hsa04660)
LIG_SH2_STAT5 LAT_HUMAN161164BinaryPhysicochemical compatibilityPhosphorylation of Y161 in the SH2-binding motif of Linker for activation of T-cells family member 1 (LAT) induces binding to the 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma-1 (PLCG1) protein.
details
Curated

TCR signaling (Reactome - 202403)
LIG_SH2_STAT5 LAT_HUMAN161164BinaryPhysicochemical compatibilityPhosphorylation of Y161 in the SH2-binding motif of Linker for activation of T-cells family member 1 (LAT) induces binding to the 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma-1 (PLCG1) protein.
details
Curated
           
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