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UNIPROT:P20963 (12 hits)
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Pathway evidence source
Curated
inferred
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Index
T cell receptor signaling pathway
TCR signaling
Motif
Protein
Start
End
Switch Type
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Information
Evidence
T cell receptor signaling pathway
(
KEGG - hsa04660
)
LIG_TYR_ITAM
CD3Z_HUMAN
69
86
Avidity‑sensing
Phosphorylation of Y72 and Y83 in the ITAM motif of
T-cell surface glycoprotein CD3 zeta chain (CD247)
induces high-avidity binding to the tandem SH2 domains of
Tyrosine-protein kinase ZAP-70 (ZAP70)
.
details
Curated
LIG_TYR_ITAM
CD3Z_HUMAN
69
86
Avidity‑sensing
Phosphorylation of Y72 and Y83 in the ITAM motif of
T-cell surface glycoprotein CD3 zeta chain (CD247)
induces high-avidity binding to the tandem SH2 domains of
Tyrosine-protein kinase ZAP-70 (ZAP70)
.
details
Curated
LIG_TYR_ITAM
CD3Z_HUMAN
108
126
Avidity‑sensing
Phosphorylation of Y111 and Y123 in the ITAM motif of
T-cell surface glycoprotein CD3 zeta chain (CD247)
induces high-avidity binding to the tandem SH2 domains of
Tyrosine-protein kinase ZAP-70 (ZAP70)
.
details
Curated
LIG_TYR_ITAM
CD3Z_HUMAN
108
126
Avidity‑sensing
Phosphorylation of Y111 and Y123 in the ITAM motif of
T-cell surface glycoprotein CD3 zeta chain (CD247)
induces high-avidity binding to the tandem SH2 domains of
Tyrosine-protein kinase ZAP-70 (ZAP70)
.
details
Curated
LIG_TYR_ITAM
CD3Z_HUMAN
139
156
Avidity‑sensing
Phosphorylation of Y142 and Y153 in the ITAM motif of
T-cell surface glycoprotein CD3 zeta chain (CD247)
induces high-avidity binding to the tandem SH2 domains of
Tyrosine-protein kinase ZAP-70 (ZAP70)
.
details
Curated
LIG_TYR_ITAM
CD3Z_HUMAN
139
156
Avidity‑sensing
Phosphorylation of Y142 and Y153 in the ITAM motif of
T-cell surface glycoprotein CD3 zeta chain (CD247)
induces high-avidity binding to the tandem SH2 domains of
Tyrosine-protein kinase ZAP-70 (ZAP70)
.
details
Curated
TCR signaling
(
Reactome - 202403
)
LIG_TYR_ITAM
CD3Z_HUMAN
69
86
Avidity‑sensing
Phosphorylation of Y72 and Y83 in the ITAM motif of
T-cell surface glycoprotein CD3 zeta chain (CD247)
induces high-avidity binding to the tandem SH2 domains of
Tyrosine-protein kinase ZAP-70 (ZAP70)
.
details
Curated
LIG_TYR_ITAM
CD3Z_HUMAN
69
86
Avidity‑sensing
Phosphorylation of Y72 and Y83 in the ITAM motif of
T-cell surface glycoprotein CD3 zeta chain (CD247)
induces high-avidity binding to the tandem SH2 domains of
Tyrosine-protein kinase ZAP-70 (ZAP70)
.
details
Curated
LIG_TYR_ITAM
CD3Z_HUMAN
108
126
Avidity‑sensing
Phosphorylation of Y111 and Y123 in the ITAM motif of
T-cell surface glycoprotein CD3 zeta chain (CD247)
induces high-avidity binding to the tandem SH2 domains of
Tyrosine-protein kinase ZAP-70 (ZAP70)
.
details
Curated
LIG_TYR_ITAM
CD3Z_HUMAN
108
126
Avidity‑sensing
Phosphorylation of Y111 and Y123 in the ITAM motif of
T-cell surface glycoprotein CD3 zeta chain (CD247)
induces high-avidity binding to the tandem SH2 domains of
Tyrosine-protein kinase ZAP-70 (ZAP70)
.
details
Curated
LIG_TYR_ITAM
CD3Z_HUMAN
139
156
Avidity‑sensing
Phosphorylation of Y142 and Y153 in the ITAM motif of
T-cell surface glycoprotein CD3 zeta chain (CD247)
induces high-avidity binding to the tandem SH2 domains of
Tyrosine-protein kinase ZAP-70 (ZAP70)
.
details
Curated
LIG_TYR_ITAM
CD3Z_HUMAN
139
156
Avidity‑sensing
Phosphorylation of Y142 and Y153 in the ITAM motif of
T-cell surface glycoprotein CD3 zeta chain (CD247)
induces high-avidity binding to the tandem SH2 domains of
Tyrosine-protein kinase ZAP-70 (ZAP70)
.
details
Curated
