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Group by :Switch typeMotif classProteinEnzymePathway            Group Index    Colouring Info              Filtered: IPR:IPR000980 (10 hits) x
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  Domain hiding  Altered binding specificity  Motif hiding  Composite binding site formation
  Uncategorised  Rheostatic  Allostery  Avidity-sensing
  Physicochemical compatibility  Pre-translational  Competition

x  Index
Epidermal growth factor receptorInterferon alpha/beta receptor 1Receptor tyrosine-protein kinase erbB-2
Receptor tyrosine-protein kinase erbB-3Tyrosine-protein kinase SYKTyrosine-protein kinase ZAP-70


MotifStartEndSwitch TypeSwitch SubtypeSwitch DescriptionInformation

Epidermal growth factor receptor - EGFR -  Homo sapiens
LIG_SH2_IE10111020BinaryPhysicochemical compatibilityPhosphorylation of Y1016 in the SH2-binding motif of Epidermal growth factor receptor (EGFR) induces binding to the Ras and Rab interactor 1 (RIN1) protein.
details
LIG_SH2_IE11911200BinaryPhysicochemical compatibilityPhosphorylation of Y1197 in the SH2-binding motif of Epidermal growth factor receptor (EGFR) induces binding to the Ras and Rab interactor 1 (RIN1) protein.
details
LIG_SH2_IE10081024BinaryPhysicochemical compatibilityPhosphorylation of Y1016 in the SH2-binding motif of Epidermal growth factor receptor (EGFR) induces binding to the Tyrosine-protein kinase JAK1 (JAK1) protein.
details

Interferon alpha/beta receptor 1 - IFNAR1 -  Homo sapiens
LIG_SH2_IE458474BinaryPhysicochemical compatibilityPhosphorylation of Y466 in the SH2-binding motif of Interferon alpha/beta receptor 1 (IFNAR1) induces binding to the Non-receptor tyrosine-protein kinase TYK2 (TYK2) protein.
details
LIG_SH2_IE473489BinaryPhysicochemical compatibilityPhosphorylation of Y481 in the SH2-binding motif of Interferon alpha/beta receptor 1 (IFNAR1) induces binding to the Non-receptor tyrosine-protein kinase TYK2 (TYK2) protein.
details

Receptor tyrosine-protein kinase erbB-2 - ERBB2 -  Homo sapiens
LIG_SH2_IE10151031BinaryPhysicochemical compatibilityPhosphorylation of Y1023 in the SH2-binding motif of Receptor tyrosine-protein kinase erbB-2 (ERBB2) induces binding to the Tyrosine-protein kinase JAK1 (JAK1) protein.
details

Receptor tyrosine-protein kinase erbB-3 - ERBB3 -  Homo sapiens
LIG_SH2_IE13201336BinaryPhysicochemical compatibilityPhosphorylation of Y1328 in the SH2-binding motif of Receptor tyrosine-protein kinase erbB-3 (ERBB3) induces binding to the Tyrosine-protein kinase JAK1 (JAK1) protein.
details
LIG_SH2_IE12681284BinaryPhysicochemical compatibilityPhosphorylation of Y1276 in the SH2-binding motif of Receptor tyrosine-protein kinase erbB-3 (ERBB3) induces binding to the Tyrosine-protein kinase JAK3 (JAK3) protein.
details

Tyrosine-protein kinase SYK - SYK -  Homo sapiens
LIG_SH2_IIC315331BinaryPhysicochemical compatibilityPhosphorylation of Y323 in the SH2-binding motif of Tyrosine-protein kinase SYK (SYK) induces binding to the E3 ubiquitin-protein ligase CBL-B (CBLB) protein.
details

Tyrosine-protein kinase ZAP-70 - ZAP70 -  Homo sapiens
LIG_SH2_IIC284300BinaryPhysicochemical compatibilityPhosphorylation of Y292 in the SH2-binding motif of Tyrosine-protein kinase ZAP-70 (ZAP70) induces binding to the E3 ubiquitin-protein ligase CBL-B (CBLB) protein.
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