switches.ELM

Group by :Switch type Motif class Protein Enzyme Pathway Group Index Colouring Info Filtered: UNIPROT:Q9HBL0 (2 hits) x

x Coloured by switch type.

Domain hiding	Altered binding specificity	Motif hiding	Composite binding site formation
Uncategorised	Rheostatic	Allostery	Avidity-sensing
Physicochemical compatibility	Pre-translational	Competition

x Index

Motif

Start

End

Switch Type

Switch Subtype

Switch Description

Information

3-phosphoinositide-dependent protein kinase 1 - PDPK1 - Homo sapiens
LIG_SH2_IC	376	379	Binary	Physicochemical compatibility	Phosphorylation of Y376 in the SH2-binding motif of 3-phosphoinositide-dependent protein kinase 1 (PDPK1) induces binding to the Tensin-1 (TNS1) protein.	details
Docking protein 2 - DOK2 - Homo sapiens
LIG_SH2_IC	402	405	Binary	Physicochemical compatibility	Phosphorylation of Y402 in the SH2-binding motif of Docking protein 2 (DOK2) induces binding to the Tensin-1 (TNS1) protein.	details