switches
.ELM
About
Help
Definitions
Submit
Search
Analyse
Browse
Home
Group by :
Switch type
Motif class
Protein
Enzyme
Pathway
         
Hide inferred
  
Group Index
  
Colouring Info
             
Filtered:
PFAM:PF07653 (10 hits)
x
submit
x
  
Coloured by:
Modifier evidence source
        
 
Curated        
 
inferred
x
  
Index
Cyclin-dependent kinase 5
GSK-3 subfamily
()
Mitogen-activated protein kinase 1
Mitogen-activated protein kinase 10
Mitogen-activated protein kinase 3
(Rattus)
Mitogen-activated protein kinase 8
Mitogen-activated protein kinase 9
NP_446294
(?)
Serine/threonine-protein kinase mTOR
Motif
Protein
Start
End
Switch Type
Switch Subtype
Switch description
Information
Evidence
GSK-3 subfamily
LIG_SH3_2
MYC_HUMAN
60
65
Binary
Physicochemical compatibility
Phosphorylation of S62 in the SH3-binding motif of
Myc proto-oncogene protein (MYC)
by
GSK-3 subfamily
disrupts its interaction with
Myc box-dependent-interacting protein 1 (BIN1)
.
details
Curated
Cyclin-dependent kinase 5 -
CDK5
-  
Homo sapiens
LIG_SH3_2
MYC_HUMAN
60
65
Binary
Physicochemical compatibility
Phosphorylation of S62 in the SH3-binding motif of
Myc proto-oncogene protein (MYC)
by
GSK-3 subfamily
disrupts its interaction with
Myc box-dependent-interacting protein 1 (BIN1)
.
details
Inferred
Mitogen-activated protein kinase 1 -
MAPK1
-  
Homo sapiens
LIG_SH3_2
MYC_HUMAN
60
65
Binary
Physicochemical compatibility
Phosphorylation of S62 in the SH3-binding motif of
Myc proto-oncogene protein (MYC)
by
GSK-3 subfamily
disrupts its interaction with
Myc box-dependent-interacting protein 1 (BIN1)
.
details
Inferred
LIG_SH3_2
MYC_HUMAN
60
65
Binary
Physicochemical compatibility
Phosphorylation of S62 in the SH3-binding motif of
Myc proto-oncogene protein (MYC)
by
GSK-3 subfamily
disrupts its interaction with
Myc box-dependent-interacting protein 1 (BIN1)
.
details
Inferred
Mitogen-activated protein kinase 10 -
MAPK10
-  
Homo sapiens
LIG_SH3_2
MYC_HUMAN
60
65
Binary
Physicochemical compatibility
Phosphorylation of S62 in the SH3-binding motif of
Myc proto-oncogene protein (MYC)
by
GSK-3 subfamily
disrupts its interaction with
Myc box-dependent-interacting protein 1 (BIN1)
.
details
Inferred
Mitogen-activated protein kinase 3 -
MAPK3
-  
Rattus norvegicus
LIG_SH3_2
MYC_HUMAN
60
65
Binary
Physicochemical compatibility
Phosphorylation of S62 in the SH3-binding motif of
Myc proto-oncogene protein (MYC)
by
GSK-3 subfamily
disrupts its interaction with
Myc box-dependent-interacting protein 1 (BIN1)
.
details
Inferred
Mitogen-activated protein kinase 8 -
MAPK8
-  
Homo sapiens
LIG_SH3_2
MYC_HUMAN
60
65
Binary
Physicochemical compatibility
Phosphorylation of S62 in the SH3-binding motif of
Myc proto-oncogene protein (MYC)
by
GSK-3 subfamily
disrupts its interaction with
Myc box-dependent-interacting protein 1 (BIN1)
.
details
Inferred
Mitogen-activated protein kinase 9 -
MAPK9
-  
Homo sapiens
LIG_SH3_2
MYC_HUMAN
60
65
Binary
Physicochemical compatibility
Phosphorylation of S62 in the SH3-binding motif of
Myc proto-oncogene protein (MYC)
by
GSK-3 subfamily
disrupts its interaction with
Myc box-dependent-interacting protein 1 (BIN1)
.
details
Inferred
NP_446294 -
?
-  
?
LIG_SH3_2
MYC_HUMAN
60
65
Binary
Physicochemical compatibility
Phosphorylation of S62 in the SH3-binding motif of
Myc proto-oncogene protein (MYC)
by
GSK-3 subfamily
disrupts its interaction with
Myc box-dependent-interacting protein 1 (BIN1)
.
details
Inferred
Serine/threonine-protein kinase mTOR -
MTOR
-  
Homo sapiens
LIG_SH3_2
MYC_HUMAN
60
65
Binary
Physicochemical compatibility
Phosphorylation of S62 in the SH3-binding motif of
Myc proto-oncogene protein (MYC)
by
GSK-3 subfamily
disrupts its interaction with
Myc box-dependent-interacting protein 1 (BIN1)
.
details
Inferred