switches.ELM

Group by :Switch type Motif class Protein Enzyme Pathway Group Index Colouring Info Filtered: UNIPROT:P20936 (2 hits) x

x Coloured by switch type.

Domain hiding	Altered binding specificity	Motif hiding	Composite binding site formation
Uncategorised	Rheostatic	Allostery	Avidity-sensing
Physicochemical compatibility	Pre-translational	Competition

x Index

Protein

Start

End

Switch Type

Switch Subtype

Switch Description

Information

LIG_SH2_IB -
PAXI_HUMAN	118	121	Binary	Pre‑translational	Alternative splicing removes the SH2-binding motif of Paxillin (PXN), abrogating binding to Ras GTPase-activating protein 1 (RASA1).	details
PAXI_HUMAN	118	121	Binary	Pre‑translational	Alternative splicing removes the SH2-binding motif of Paxillin (PXN), abrogating binding to Ras GTPase-activating protein 1 (RASA1).	details