Domain hiding |   Altered binding specificity |   Motif hiding |   Composite binding site formation |
  Uncategorised |   Rheostatic |   Allostery |   Avidity-sensing |
  Physicochemical compatibility |   Pre-translational |   Competition |
Protein | Start | End | Switch Type | Switch Subtype | Switch Description | Information |
TRG_ER_KDEL_1 - Golgi-to-ER retrieving signal found at the C-terminus of many ER soluble proteins. It interacts with the KDEL receptor which in turns interacts with components of the coatomer (COP I). | |||||||
PIMT_BOVIN | 225 | 228 | Binary | Pre‑translational | Alternative splicing removes the KDEL ER-retention motif of Isoform 2 of Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT1). | ||
P3H1_HUMAN | 733 | 736 | Binary | Pre‑translational | Alternative splicing removes the KDEL ER-retention motif of Prolyl 3-hydroxylase 1 (LEPRE1). |