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Group by :Switch type Motif class Protein Enzyme Pathway Group Index Colouring Info Filtered: UNIPROT:P20936 (2 hits) x

x Coloured by switch type.

Domain hiding	Altered binding specificity	Motif hiding	Composite binding site formation
Uncategorised	Rheostatic	Allostery	Avidity-sensing
Physicochemical compatibility	Pre-translational	Competition

x Index

Type: Binary Subtype: Pre‑translational

Protein

Motif

Start

End

Switch description

Information

*Type:* Binary *Subtype:* Pre‑translational
Pre-translational mechanisms such as alternative splicing, alternative promoter-usage and/or RNA editing result in inclusion or removal of exons that contain an entire or partial motif.
PAXI_HUMAN	LIG_SH2_IB	118	121	Alternative splicing removes the SH2-binding motif of Paxillin (PXN), abrogating binding to Ras GTPase-activating protein 1 (RASA1).	details
PAXI_HUMAN	LIG_SH2_IB	118	121	Alternative splicing removes the SH2-binding motif of Paxillin (PXN), abrogating binding to Ras GTPase-activating protein 1 (RASA1).	details

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