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Group by :Switch typeMotif classProteinEnzymePathway         Hide inferred   Group Index    Colouring Info              Filtered: UNIPROT:P02751 (10 hits) x
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x  Coloured by: Pathway evidence source
          Curated          inferred


x  Index
ECM-receptor interactionFocal adhesionPI3K-Akt signaling pathway
PhagosomeRegulation of actin cytoskeleton


MotifProteinStartEndSwitch TypeSwitch SubtypeSwitch descriptionInformationEvidence

ECM-receptor interaction (KEGG - hsa04512)
LIG_RGD FINC_HUMAN15241526Pre‑assemblyComposite binding site formationBinding of Fibronectin (FN1) to integrin receptors depends on pre-assembly of Integrin alpha-V (ITGAV)-Integrin beta-3 (ITGB3) heterodimers, since association of the integrin alpha and beta subunits results in the formation of a composite binding site for the RGD motif in the ligand.
details
Inferred
LIG_Integrin_isoDGR_1 FINC_HUMAN263265Pre‑assemblyComposite binding site formationBinding of Fibronectin (FN1) to integrin receptors depends on pre-assembly of Integrin alpha-V (ITGAV)-Integrin beta-3 (ITGB3) heterodimers, since association of the integrin alpha and beta subunits results in the formation of a composite binding site for the RGD motif in the ligand.
details
Inferred

Focal adhesion (KEGG - hsa04510)
LIG_RGD FINC_HUMAN15241526Pre‑assemblyComposite binding site formationBinding of Fibronectin (FN1) to integrin receptors depends on pre-assembly of Integrin alpha-V (ITGAV)-Integrin beta-3 (ITGB3) heterodimers, since association of the integrin alpha and beta subunits results in the formation of a composite binding site for the RGD motif in the ligand.
details
Inferred
LIG_Integrin_isoDGR_1 FINC_HUMAN263265Pre‑assemblyComposite binding site formationBinding of Fibronectin (FN1) to integrin receptors depends on pre-assembly of Integrin alpha-V (ITGAV)-Integrin beta-3 (ITGB3) heterodimers, since association of the integrin alpha and beta subunits results in the formation of a composite binding site for the RGD motif in the ligand.
details
Inferred

PI3K-Akt signaling pathway (KEGG - hsa04151)
LIG_RGD FINC_HUMAN15241526Pre‑assemblyComposite binding site formationBinding of Fibronectin (FN1) to integrin receptors depends on pre-assembly of Integrin alpha-V (ITGAV)-Integrin beta-3 (ITGB3) heterodimers, since association of the integrin alpha and beta subunits results in the formation of a composite binding site for the RGD motif in the ligand.
details
Inferred
LIG_Integrin_isoDGR_1 FINC_HUMAN263265Pre‑assemblyComposite binding site formationBinding of Fibronectin (FN1) to integrin receptors depends on pre-assembly of Integrin alpha-V (ITGAV)-Integrin beta-3 (ITGB3) heterodimers, since association of the integrin alpha and beta subunits results in the formation of a composite binding site for the RGD motif in the ligand.
details
Inferred

Phagosome (KEGG - hsa04145)
LIG_RGD FINC_HUMAN15241526Pre‑assemblyComposite binding site formationBinding of Fibronectin (FN1) to integrin receptors depends on pre-assembly of Integrin alpha-V (ITGAV)-Integrin beta-3 (ITGB3) heterodimers, since association of the integrin alpha and beta subunits results in the formation of a composite binding site for the RGD motif in the ligand.
details
Inferred
LIG_Integrin_isoDGR_1 FINC_HUMAN263265Pre‑assemblyComposite binding site formationBinding of Fibronectin (FN1) to integrin receptors depends on pre-assembly of Integrin alpha-V (ITGAV)-Integrin beta-3 (ITGB3) heterodimers, since association of the integrin alpha and beta subunits results in the formation of a composite binding site for the RGD motif in the ligand.
details
Inferred

Regulation of actin cytoskeleton (KEGG - hsa04810)
LIG_RGD FINC_HUMAN15241526Pre‑assemblyComposite binding site formationBinding of Fibronectin (FN1) to integrin receptors depends on pre-assembly of Integrin alpha-V (ITGAV)-Integrin beta-3 (ITGB3) heterodimers, since association of the integrin alpha and beta subunits results in the formation of a composite binding site for the RGD motif in the ligand.
details
Inferred
LIG_Integrin_isoDGR_1 FINC_HUMAN263265Pre‑assemblyComposite binding site formationBinding of Fibronectin (FN1) to integrin receptors depends on pre-assembly of Integrin alpha-V (ITGAV)-Integrin beta-3 (ITGB3) heterodimers, since association of the integrin alpha and beta subunits results in the formation of a composite binding site for the RGD motif in the ligand.
details
Inferred
           
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