Switch #: SWTI000058

Switch type: Binary

Switch subtype: Physicochemical compatibility

Description:
Phosphorylation of S115 in the Pin1-binding motif of Tyrosine-protein kinase BTK (Btk) induces binding to the Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 (Pin1) protein.

Participants:
(1) Tyrosine-protein kinase BTK (Btk)
(2) Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 (Pin1)

(1) Regulation of Bruton tyrosine kinase by the peptidylprolyl isomerase Pin1.
Yu et al. J. Biol. Chem. (2006)

Other switches involving participants
Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 (Pin1) - 28 more (view)
Tyrosine-protein kinase BTK (Btk) - 1 more (view)

Other switches involving interfaces
DOC_WW_Pin1_4 - 90 more (view)
WW domain - 105 more (view)