Switch #: SWTI000065

Switch type: Binary

Switch subtype: Physicochemical compatibility

Description:
Phosphorylation of T149 in the Pin1-binding motif of Telomeric repeat-binding factor 1 (TERF1) induces binding to the Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 (PIN1) protein.

Participants:
(1) Telomeric repeat-binding factor 1 (TERF1)
(2) Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 (PIN1)

(1) Essential role of Pin1 in the regulation of TRF1 stability and telomere maintenance.
Lee et al. Nat. Cell Biol. (2009)

Other switches involving participants
Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 (PIN1) - 55 more (view)

Other switches involving interfaces
DOC_WW_Pin1_4 - 90 more (view)
WW domain - 105 more (view)