Switch #: SWTI000133

Switch type: Binary

Switch subtype: Physicochemical compatibility

Description:
Phosphorylation of T645 in the FHA-binding motif of Mediator of replication checkpoint protein 1 (mrc1) induces binding to the Serine/threonine-protein kinase cds1 (cds1) protein.

Participants:
(1) Mediator of replication checkpoint protein 1 (mrc1)
(2) Serine/threonine-protein kinase cds1 (cds1)

(1) Replication checkpoint protein Mrc1 is regulated by Rad3 and Tel1 in fission yeast.
Zhao et al. Mol. Cell. Biol. (2003)

Other switches involving interfaces
FHA domain - 11 more (view)
LIG_FHA_2 - 9 more (view)