Switch #: SWTI000478

Switch type: Binary

Switch subtype: Pre-translational

Description:
Alternative splicing removes the Clathrin II-binding motif of Myc box-dependent-interacting protein 1 (BIN1), abrogating binding to Clathrin heavy chain 1 (CLTC).

Participants:
(1) Myc box-dependent-interacting protein 1 (BIN1)
(2) Clathrin heavy chain 1 (CLTC)

(1) Multiple amphiphysin II splice variants display differential clathrin binding: identification of two distinct clathrin-binding sites.
Ramjaun et al. J. Neurochem. (1998)

Other switches involving participants
Myc box-dependent-interacting protein 1 (BIN1) - 2 more (view)
Clathrin heavy chain 1 (CLTC) - 4 more (view)

Other switches involving interfaces
Clathrin propeller repeat - 4 more (view)
LIG_Clathr_ClatBox_2 - 2 more (view)