Switch #: SWTI000499

Switch type: Binary

Switch subtype: Pre-translational

Description:
Alternative splicing removes the PDZ-binding motif of Isoform 5-HT4(E) of 5-hydroxytryptamine receptor 4 (Htr4), abrogating binding to InaD-like protein (Inadl).

Participants:
(1) Isoform 5-HT4(E) of 5-hydroxytryptamine receptor 4 (Htr4)
(2) InaD-like protein (Inadl)

(1) New sorting nexin (SNX27) and NHERF specifically interact with the 5-HT4a receptor splice variant: roles in receptor targeting.
Joubert et al. J. Cell. Sci. (2004)

Other switches involving interfaces
LIG_PDZ_Class_2 - 3 more (view)
PDZ domain (Also known as DHR or GLGF) - 45 more (view)