switches.ELM

Group by :Switch type Motif class Protein Enzyme Pathway Hide inferred Group Index Colouring Info Filtered: PFAM:PF00630 (8 hits) x

x Coloured by: Modifier evidence source
Curated inferred

x Index

Protein kinase C alpha type	Protein kinase C beta type	Protein kinase C beta type
Protein kinase C delta type	Protein kinase C eta type

Motif

Protein

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End

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Information

Evidence

Protein kinase C alpha type - PRKCA - Homo sapiens
LIG_Filamin	ITB2_HUMAN	753	763	Specificity	Altered binding specificity	Phosphorylation of T758 in Integrin beta-2 (ITGB2) switches the specificity of ITGB2 from Filamin-A (FLNA) to 14-3-3 proteins (e.g. 14-3-3 protein zeta/delta (YWHAZ)).	details	Inferred
LIG_Filamin	ITB2_HUMAN	753	763	Specificity	Altered binding specificity	Phosphorylation of T758 in Integrin beta-2 (ITGB2) switches the specificity of ITGB2 from Filamin-A (FLNA) to 14-3-3 proteins (e.g. 14-3-3 protein zeta/delta (YWHAZ)).	details	Inferred
Protein kinase C beta type - PRKCB - Homo sapiens
LIG_Filamin	ITB2_HUMAN	753	763	Specificity	Altered binding specificity	Phosphorylation of T758 in Integrin beta-2 (ITGB2) switches the specificity of ITGB2 from Filamin-A (FLNA) to 14-3-3 proteins (e.g. 14-3-3 protein zeta/delta (YWHAZ)).	details	Inferred
Protein kinase C beta type - PRKCB - Homo sapiens
LIG_Filamin	ITB2_HUMAN	753	763	Specificity	Altered binding specificity	Phosphorylation of T758 in Integrin beta-2 (ITGB2) switches the specificity of ITGB2 from Filamin-A (FLNA) to 14-3-3 proteins (e.g. 14-3-3 protein zeta/delta (YWHAZ)).	details	Inferred
Protein kinase C delta type - PRKCD - Homo sapiens
LIG_Filamin	ITB2_HUMAN	753	763	Specificity	Altered binding specificity	Phosphorylation of T758 in Integrin beta-2 (ITGB2) switches the specificity of ITGB2 from Filamin-A (FLNA) to 14-3-3 proteins (e.g. 14-3-3 protein zeta/delta (YWHAZ)).	details	Inferred
LIG_Filamin	ITB2_HUMAN	753	763	Specificity	Altered binding specificity	Phosphorylation of T758 in Integrin beta-2 (ITGB2) switches the specificity of ITGB2 from Filamin-A (FLNA) to 14-3-3 proteins (e.g. 14-3-3 protein zeta/delta (YWHAZ)).	details	Inferred
Protein kinase C eta type - PRKCH - Homo sapiens
LIG_Filamin	ITB2_HUMAN	753	763	Specificity	Altered binding specificity	Phosphorylation of T758 in Integrin beta-2 (ITGB2) switches the specificity of ITGB2 from Filamin-A (FLNA) to 14-3-3 proteins (e.g. 14-3-3 protein zeta/delta (YWHAZ)).	details	Inferred
LIG_Filamin	ITB2_HUMAN	753	763	Specificity	Altered binding specificity	Phosphorylation of T758 in Integrin beta-2 (ITGB2) switches the specificity of ITGB2 from Filamin-A (FLNA) to 14-3-3 proteins (e.g. 14-3-3 protein zeta/delta (YWHAZ)).	details	Inferred