Motif | Protein | Start | End | Switch Type | Switch Subtype | Switch description | Information | Evidence |
Proto-oncogene tyrosine-protein kinase Src - SRC -  Homo sapiens | ||||||||
TRG_ENDOCYTIC_2 | L1CAM_HUMAN | 1176 | 1179 | Binary | Physicochemical compatibility | Phosphorylation of Y1176 by Proto-oncogene tyrosine-protein kinase Src (SRC) in the endocytosis motif of Neural cell adhesion molecule L1 (L1CAM) inhibits binding to AP-2 complex subunit mu (AP2M1). | Curated | |
TRG_ENDOCYTIC_2 | L1CAM_HUMAN | 1176 | 1179 | Binary | Physicochemical compatibility | Phosphorylation of Y1176 in the endocytotic motif of Neural cell adhesion molecule L1 (L1CAM) by Proto-oncogene tyrosine-protein kinase Src (SRC) abolishes binding to the AP-2 complex subunit mu (AP2M1) and thereby inhibits internalisation of Neural cell adhesion molecule L1 (L1CAM). | Curated |