switches.ELM

Group by :Switch type Motif class Protein Enzyme Pathway Hide inferred Group Index Colouring Info Filtered: UNIPROT:P42229 (11 hits) x

x Coloured by: Modifier evidence source
Curated inferred

x Index

Proto-oncogene tyrosine-protein kinase Src	Tyrosine-protein kinase JAK2	Tyrosine-protein kinase JAK3
Tyrosine-protein kinase Lck	Tyrosine-protein kinase Lyn	Tyrosine-protein kinase Lyn (Mus)
Tyrosine-protein kinase SYK

Motif

Protein

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Information

Evidence

Proto-oncogene tyrosine-protein kinase Src - SRC - Homo sapiens
LIG_SH2_III	STA5A_HUMAN	686	702	Binary	Physicochemical compatibility	Phosphorylation of Y694 in the SH2-binding motif of Signal transducer and activator of transcription 5A (STAT5A) induces binding to the Signal transducer and activator of transcription 5B (STAT5B) protein.	details	Inferred
LIG_SH2_III	STA5A_HUMAN	686	702	Binary	Physicochemical compatibility	Phosphorylation of Y694 in the SH2-binding motif of Signal transducer and activator of transcription 5A (STAT5A) induces binding to the Signal transducer and activator of transcription 5B (STAT5B) protein.	details	Inferred
Tyrosine-protein kinase JAK2 - JAK2 - Homo sapiens
LIG_SH2_III	STA5A_HUMAN	686	702	Binary	Physicochemical compatibility	Phosphorylation of Y694 in the SH2-binding motif of Signal transducer and activator of transcription 5A (STAT5A) induces binding to the Signal transducer and activator of transcription 5B (STAT5B) protein.	details	Inferred
LIG_SH2_III	STA5A_HUMAN	686	702	Binary	Physicochemical compatibility	Phosphorylation of Y694 in the SH2-binding motif of Signal transducer and activator of transcription 5A (STAT5A) induces binding to the Signal transducer and activator of transcription 5B (STAT5B) protein.	details	Inferred
Tyrosine-protein kinase JAK3 - JAK3 - Homo sapiens
LIG_SH2_III	STA5A_HUMAN	686	702	Binary	Physicochemical compatibility	Phosphorylation of Y694 in the SH2-binding motif of Signal transducer and activator of transcription 5A (STAT5A) induces binding to the Signal transducer and activator of transcription 5B (STAT5B) protein.	details	Inferred
Tyrosine-protein kinase Lck - LCK - Homo sapiens
LIG_SH2_III	IL2RB_HUMAN	531	540	Binary	Physicochemical compatibility	Phosphorylation of Y536 in the SH2-binding motif of Interleukin-2 receptor subunit beta (IL2RB) induces binding to the Signal transducer and activator of transcription 5A (STAT5A) protein.	details	Inferred
LIG_SH2_III	IL2RB_HUMAN	531	540	Binary	Physicochemical compatibility	Phosphorylation of Y536 in the SH2-binding motif of Interleukin-2 receptor subunit beta (IL2RB) induces binding to the Signal transducer and activator of transcription 5A (STAT5A) protein.	details	Inferred
LIG_SH2_III	STA5A_HUMAN	686	702	Binary	Physicochemical compatibility	Phosphorylation of Y694 in the SH2-binding motif of Signal transducer and activator of transcription 5A (STAT5A) induces binding to the Signal transducer and activator of transcription 5B (STAT5B) protein.	details	Inferred
Tyrosine-protein kinase Lyn - LYN - Homo sapiens
LIG_SH2_III	STA5A_HUMAN	686	702	Binary	Physicochemical compatibility	Phosphorylation of Y694 in the SH2-binding motif of Signal transducer and activator of transcription 5A (STAT5A) induces binding to the Signal transducer and activator of transcription 5B (STAT5B) protein.	details	Inferred
Tyrosine-protein kinase Lyn - LYN - Mus musculus
LIG_SH2_III	STA5A_HUMAN	686	702	Binary	Physicochemical compatibility	Phosphorylation of Y694 in the SH2-binding motif of Signal transducer and activator of transcription 5A (STAT5A) induces binding to the Signal transducer and activator of transcription 5B (STAT5B) protein.	details	Inferred
Tyrosine-protein kinase SYK - SYK - Homo sapiens
LIG_SH2_III	STA5A_HUMAN	686	702	Binary	Physicochemical compatibility	Phosphorylation of Y694 in the SH2-binding motif of Signal transducer and activator of transcription 5A (STAT5A) induces binding to the Signal transducer and activator of transcription 5B (STAT5B) protein.	details	Inferred