Motif | Protein | Start | End | Switch Type | Switch Subtype | Switch description | Information | Evidence |
PKC subfamily | ||||||||
TRG_ER_diArg_1 | NMDZ1_HUMAN | 893 | 895 | Binary | Physicochemical compatibility | Phosphorylation of S896 adjacent to the ER retention motif of Glutamate [NMDA] receptor subunit zeta-1 (GRIN1) by PKC subfamily (and possibly S897 by PKA) inactivates the motif and promotes delivery of the receptor to the plasma membrane. Optimal trafficking upon dual phosphorylation of S896 and S897 allows regulation of receptor trafficking by coordinated PKA and PKC signaling. | Curated |