Motif | Protein | Start | End | Switch Type | Switch Subtype | Switch description | Information | Evidence |
Peroxisome (KEGG - hsa04146) | ||||||||
TRG_PTS1 | AMACR_HUMAN | 379 | 382 | Binary | Pre‑translational | Alternative splicing removes the type 1 peroxisomal targeting signal (PTS1) of Alpha-methylacyl-CoA racemase (AMACR), abrogating binding to Peroxisomal targeting signal 1 receptor (PEX5) and import into the peroxisome. Only the major AMACR IA (also known as Isoform 1 of Alpha-methylacyl-CoA racemase (AMACR)) form localises to the peroxisome. | Inferred |