Motif | Protein | Start | End | Switch Type | Switch Subtype | Switch description | Information | Evidence |
Kinetochore capture of astral microtubules (Reactome - 375302) | ||||||||
LIG_SxIP_EBH_1 | KIF2C_HUMAN | 93 | 104 | Binary | Physicochemical compatibility | Phosphorylation of S95 and S109 and S111 adjacent to the EB1-binding motif of Kinesin-like protein KIF2C (KIF2C) by Aurora kinase B (AURKB) and Aurora kinase B (AURKB) and Aurora kinase B (AURKB) inhibits its interaction with Microtubule-associated protein RP/EB family member 1 (MAPRE1), thereby inhibiting microtubule tip tracking. | Curated | |
LIG_SxIP_EBH_1 | CLAP2_HUMAN | 515 | 525 | Binary | Physicochemical compatibility | Phosphorylation of several serine residues surrounding the EB1-binding motifs of CLIP-associating protein 2 (CLASP2) by Glycogen synthase kinase-3 beta (GSK3B) and Glycogen synthase kinase-3 beta (GSK3B) and Glycogen synthase kinase-3 beta (GSK3B) and Glycogen synthase kinase-3 beta (GSK3B) and Glycogen synthase kinase-3 beta (GSK3B) inhibits its interaction with Microtubule-associated protein RP/EB family member 1 (MAPRE1). | Curated |