switches.ELM

Group by :Switch type Motif class Protein Enzyme Pathway Hide inferred Group Index Colouring Info Filtered: UNIPROT:P42226 (3 hits) x

x Coloured by: Pathway evidence source
Curated inferred

x Index

Motif

Protein

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Information

Evidence

Jak-STAT signaling pathway (KEGG - hsa04630)
LIG_SH2_III	IL4RA_HUMAN	566	585	Binary	Physicochemical compatibility	Phosphorylation of Y575 in the SH2-binding motif of Interleukin-4 receptor subunit alpha (IL4R) induces binding to the Signal transducer and activator of transcription 6 (STAT6) protein.	details	Inferred
LIG_SH2_III	IL4RA_HUMAN	594	613	Binary	Physicochemical compatibility	Phosphorylation of Y603 in the SH2-binding motif of Interleukin-4 receptor subunit alpha (IL4R) induces binding to the Signal transducer and activator of transcription 6 (STAT6) protein.	details	Inferred
LIG_SH2_III	IL4RA_HUMAN	622	641	Binary	Physicochemical compatibility	Phosphorylation of Y631 in the SH2-binding motif of Interleukin-4 receptor subunit alpha (IL4R) induces binding to the Signal transducer and activator of transcription 6 (STAT6) protein.	details	Inferred