Motif | Protein | Start | End | Switch Type | Switch Subtype | Switch description | Information | Evidence |
B cell receptor signaling pathway (KEGG - hsa04662) | ||||||||
LIG_TYR_ITIM | FCG2B_HUMAN | 290 | 295 | Binary | Physicochemical compatibility | Phosphorylation of Y292 in the ITIM motif of Low affinity immunoglobulin gamma Fc region receptor II-b (FCGR2B) induces binding of Phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase 1 (INPP5D) via its SH2 domain. | Inferred | |
Fc gamma R-mediated phagocytosis (KEGG - hsa04666) | ||||||||
LIG_TYR_ITIM | FCG2B_HUMAN | 290 | 295 | Binary | Physicochemical compatibility | Phosphorylation of Y292 in the ITIM motif of Low affinity immunoglobulin gamma Fc region receptor II-b (FCGR2B) induces binding of Phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase 1 (INPP5D) via its SH2 domain. | Inferred |