switches.ELM

Group by :Switch type Motif class Protein Enzyme Pathway Hide inferred Group Index Colouring Info Filtered: UNIPROT:Q99814 (2 hits) x

x Coloured by: Pathway evidence source
Curated inferred

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Motif

Protein

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Information

Evidence

Regulation of Hypoxia-inducible Factor (HIF) by Oxygen (Reactome - 1234174)
DEG_ODPH_VHL_1	EPAS1_HUMAN	403	416	Binary	Physicochemical compatibility	Hydroxylation of P405 in the VHL-binding motif of Endothelial PAS domain-containing protein 1 (EPAS1) induces binding to the Von Hippel-Lindau disease tumor suppressor (VHL) protein.	details	Curated
DEG_ODPH_VHL_1	EPAS1_HUMAN	529	542	Binary	Physicochemical compatibility	Hydroxylation of P531 in the VHL-binding motif of Endothelial PAS domain-containing protein 1 (EPAS1) induces binding to the Von Hippel-Lindau disease tumor suppressor (VHL) protein.	details	Curated