Domain hiding |   Altered binding specificity |   Motif hiding |   Composite binding site formation |
  Uncategorised |   Rheostatic |   Allostery |   Avidity-sensing |
  Physicochemical compatibility |   Pre-translational |   Competition |
Epidermal growth factor receptor | Receptor tyrosine-protein kinase erbB-2 | Receptor tyrosine-protein kinase erbB-3 |
Motif | Start | End | Switch Type | Switch Subtype | Switch Description | Information |
Epidermal growth factor receptor - EGFR -  Homo sapiens | |||||||
LIG_SH2_IE | 1008 | 1024 | Binary | Physicochemical compatibility | Phosphorylation of Y1016 in the SH2-binding motif of Epidermal growth factor receptor (EGFR) induces binding to the Tyrosine-protein kinase JAK1 (JAK1) protein. | ||
Receptor tyrosine-protein kinase erbB-2 - ERBB2 -  Homo sapiens | |||||||
LIG_SH2_IE | 1015 | 1031 | Binary | Physicochemical compatibility | Phosphorylation of Y1023 in the SH2-binding motif of Receptor tyrosine-protein kinase erbB-2 (ERBB2) induces binding to the Tyrosine-protein kinase JAK1 (JAK1) protein. | ||
Receptor tyrosine-protein kinase erbB-3 - ERBB3 -  Homo sapiens | |||||||
LIG_SH2_IE | 1320 | 1336 | Binary | Physicochemical compatibility | Phosphorylation of Y1328 in the SH2-binding motif of Receptor tyrosine-protein kinase erbB-3 (ERBB3) induces binding to the Tyrosine-protein kinase JAK1 (JAK1) protein. |