Domain hiding | Altered binding specificity | Motif hiding | Composite binding site formation |
Uncategorised | Rheostatic | Allostery | Avidity-sensing |
Physicochemical compatibility | Pre-translational | Competition |
Motif | Start | End | Switch Type | Switch Subtype | Switch Description | Information |
Endothelial PAS domain-containing protein 1 - EPAS1 - Homo sapiens | |||||||
DEG_ODPH_VHL_1 | 403 | 416 | Binary | Physicochemical compatibility | Hydroxylation of P405 in the VHL-binding motif of Endothelial PAS domain-containing protein 1 (EPAS1) induces binding to the Von Hippel-Lindau disease tumor suppressor (VHL) protein. | ||
DEG_ODPH_VHL_1 | 529 | 542 | Binary | Physicochemical compatibility | Hydroxylation of P531 in the VHL-binding motif of Endothelial PAS domain-containing protein 1 (EPAS1) induces binding to the Von Hippel-Lindau disease tumor suppressor (VHL) protein. |