switches.ELM

Group by :Switch type Motif class Protein Enzyme Pathway Show inferred Group Index Colouring Info Filtered: ELM:TRG_NES (2 hits) x

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Curated inferred

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Protein

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Information

Evidence

Cell cycle (KEGG - hsa04110)
TRG_NES_CRM1_1	MPIP3_HUMAN	189	203	Binary	Physicochemical compatibility	Phosphorylation of S198 in the NES of M-phase inducer phosphatase 3 (CDC25C) by Serine/threonine-protein kinase PLK1 (PLK1) inhibits binding to Exportin-1 (XPO1), thus promoting nuclear localization of M-phase inducer phosphatase 3 (CDC25C).	details	Curated
G2/M Transition (Reactome - 69275)
TRG_NES_CRM1_1	MPIP3_HUMAN	189	203	Binary	Physicochemical compatibility	Phosphorylation of S198 in the NES of M-phase inducer phosphatase 3 (CDC25C) by Serine/threonine-protein kinase PLK1 (PLK1) inhibits binding to Exportin-1 (XPO1), thus promoting nuclear localization of M-phase inducer phosphatase 3 (CDC25C).	details	Curated