Switch #: SWTI000033

Switch type: Binary

Switch subtype: Physicochemical compatibility

Description:
Phosphorylation of T331 in the Pin1-binding motif of Proto-oncogene c-Fos (Fos) induces binding to the Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 (Pin1) protein.

Participants:
(1) Proto-oncogene c-Fos (Fos)
(2) Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 (Pin1)

(1) Regulation of the transcriptional activity of c-Fos by ERK. A novel role for the prolyl isomerase PIN1.
Monje et al. J. Biol. Chem. (2005)

Other switches involving participants
Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 (Pin1) - 28 more (view)
Proto-oncogene c-Fos (Fos) - 3 more (view)

Other switches involving interfaces
DOC_WW_Pin1_4 - 90 more (view)
WW domain - 105 more (view)