Interaction #1 PML - PIN1
(1) DOC_WW_Pin1_4 motif (400KKASPE405) in Protein PML (PML)
(2) WW domain (7-37) in Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 (PIN1)
PTM-dependent Induction (Phosphorylation of S403 on Protein PML (PML)) of the Protein PML (PML) DOC_WW_Pin1_4 motif - Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 (PIN1) WW domain interaction
Inferred Regulatory Enzymes for switch
Putative modifying enzymes for residue: S403 : Mitogen-activated protein kinase 7 (MAPK7).
(1) Degradation of the tumor suppressor PML by Pin1 contributes to the cancer phenotype of breast cancer MDA-MB-231 cells.
Other switches involving participants