Switch #: SWTI000072

Switch type: Binary

Switch subtype: Physicochemical compatibility

Description:
Phosphorylation of S12 in the Pin1-binding motif of POU domain, class 5, transcription factor 1 (POU5F1) induces binding to the Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 (PIN1) protein.

Participants:
(1) POU domain, class 5, transcription factor 1 (POU5F1)
(2) Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 (PIN1)

(1) A distinct role for Pin1 in the induction and maintenance of pluripotency.
Nishi et al. J. Biol. Chem. (2011)

Other switches involving participants
Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 (PIN1) - 55 more (view)

Other switches involving interfaces
DOC_WW_Pin1_4 - 90 more (view)
WW domain - 105 more (view)