Switch #: SWTI000090

Switch type: Binary

Switch subtype: Physicochemical compatibility

Description:
Phosphorylation of T452 in the Pin1-binding motif of Non-POU domain-containing octamer-binding protein (Nono) induces binding to the Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 (Pin1) protein.

Participants:
(1) Non-POU domain-containing octamer-binding protein (Nono)
(2) Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 (Pin1)

(1) The multifunctional nuclear protein p54nrb is multiphosphorylated in mitosis and interacts with the mitotic regulator Pin1.
Proteau et al. J. Mol. Biol. (2005)

Other switches involving participants
Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 (Pin1) - 28 more (view)
Non-POU domain-containing octamer-binding protein (Nono) - 2 more (view)

Other switches involving interfaces
DOC_WW_Pin1_4 - 90 more (view)
WW domain - 105 more (view)