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Switch #:
SWTI000091
Switch type:
Binary
Switch subtype:
Physicochemical compatibility

Description:
Phosphorylation of S670 in the Pin1-binding motif of Beta-adrenergic receptor kinase 1 (Adrbk1) induces binding to the Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 (Pin1) protein.

Participants:
(1) Beta-adrenergic receptor kinase 1 (Adrbk1)
(2) Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 (Pin1)

Interactions
Context
Switch localisation
ELM curated: nucleus, cytosol
References

(1) G protein-coupled receptor kinase 2 (GRK2) modulation and cell cycle progression.
Penela et al. Proc. Natl. Acad. Sci. U.S.A. (2010)

See also

Other switches involving participants
Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 (Pin1) - 28 more (view)

Other switches involving interfaces
DOC_WW_Pin1_4 - 90 more (view)
WW domain - 105 more (view)




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