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Switch #:
SWTI000092
Switch type:
Binary
Switch subtype:
Physicochemical compatibility

Description:
Phosphorylation of T8 in the Pin1-binding motif of Sulfotransferase 4A1 (SULT4A1) induces binding to the Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 (PIN1) protein.

Participants:
(1) Sulfotransferase 4A1 (SULT4A1)
(2) Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 (PIN1)

Interactions
Context
Switch localisation
ELM curated: nucleus, cytosol
References

(1) Cytosolic Aryl sulfotransferase 4A1 interacts with the peptidyl prolyl cis-trans isomerase Pin1.
Mitchell et al. Mol. Pharmacol. (2009)

(2) Phosphorylation/dephosphorylation of human SULT4A1: role of Erk1 and PP2A.
Mitchell et al. Biochim. Biophys. Acta (2011)

See also

Other switches involving participants
Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 (PIN1) - 55 more (view)
Sulfotransferase 4A1 (SULT4A1) - 1 more (view)

Other switches involving interfaces
DOC_WW_Pin1_4 - 90 more (view)
WW domain - 105 more (view)




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