Switch #: SWTI000125

Switch type: Binary

Switch subtype: Physicochemical compatibility

Description:
Phosphorylation of T603 in the FHA-binding motif of DNA repair protein RAD9 (RAD9) induces binding to the Serine/threonine-protein kinase RAD53 (RAD53) protein.

Participants:
(1) DNA repair protein RAD9 (RAD9)
(2) Serine/threonine-protein kinase RAD53 (RAD53)

(1) Solution structure of the yeast Rad53 FHA2 complexed with a phosphothreonine peptide pTXXL: comparison with the structures of FHA2-pYXL and FHA1-pTXXD complexes.
Byeon et al. J. Mol. Biol. (2001)

Other switches involving participants
Serine/threonine-protein kinase RAD53 (RAD53) - 3 more (view)
DNA repair protein RAD9 (RAD9) - 2 more (view)

Other switches involving interfaces
LIG_FHA_1 - 5 more (view)
FHA domain - 11 more (view)