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Switch #:
SWTI000124
Switch type:
Binary
Switch subtype:
Physicochemical compatibility

Description:
Phosphorylation of T68 in the FHA-binding motif of Serine/threonine-protein kinase Chk2 (CHEK2) induces binding to the Serine/threonine-protein kinase Chk2 (CHEK2) protein.

Participants:
(1) Serine/threonine-protein kinase Chk2 (CHEK2)

Interactions
Context
Switch localisation
ELM curated: nucleus
References

(1) Structural and functional versatility of the FHA domain in DNA-damage signaling by the tumor suppressor kinase Chk2.
Li et al. Mol. Cell (2002)

See also

Other switches involving interfaces
LIG_FHA_1 - 5 more (view)
FHA domain - 11 more (view)




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