Description: Phosphorylation of Y200 in the SH2-binding motif of Linker for activation of T-cells family member 1 (LAT) induces binding to the GRB2-related adaptor protein 2 (Grap2) protein.
Participants: (1) Linker for activation of T-cells family member 1 (LAT) (2) GRB2-related adaptor protein 2 (Grap2)
(1) Structural basis for differential recognition of tyrosine-phosphorylated sites in the linker for activation of T cells (LAT) by the adaptor Gads.Cho et al. EMBO J. (2004)
Other switches involving participantsLinker for activation of T-cells family member 1 (LAT) - 2 more (view)GRB2-related adaptor protein 2 (Grap2) - 1 more (view)Other switches involving interfacesSH2 domain - 140 more (view)ELM:LIG_SH2_IC - 12 more (view)
