Switch #: SWTI000401

Switch type: Binary

Switch subtype: Physicochemical compatibility

Description:
Phosphorylation of Y368 in the SH2-binding motif of Erythropoietin receptor (EPOR) induces binding to the Signal transducer and activator of transcription 5B (STAT5B) protein.

Participants:
(1) Erythropoietin receptor (EPOR)
(2) Signal transducer and activator of transcription 5B (STAT5B)

(1) Dissecting the thrombopoietin receptor: functional elements of the Mpl cytoplasmic domain.
Drachman et al. Proc. Natl. Acad. Sci. U.S.A. (1997)

Other switches involving participants
Signal transducer and activator of transcription 5B (STAT5B) - 5 more (view)
Erythropoietin receptor (EPOR) - 2 more (view)

Other switches involving interfaces
SH2 domain - 140 more (view)
ELM:LIG_SH2_III - 15 more (view)