Switch #: SWTI000433

Switch type: Binary

Switch subtype: Physicochemical compatibility

Description:
Phosphorylation of Y145 in the SH2-binding motif of Lymphocyte cytosolic protein 2 (LCP2) induces binding to the SH2 domain-containing adapter protein B (SHB) protein.

Participants:
(1) Lymphocyte cytosolic protein 2 (LCP2)
(2) SH2 domain-containing adapter protein B (SHB)

(1) Shb links SLP-76 and Vav with the CD3 complex in Jurkat T cells.
Lindholm et al. Eur. J. Biochem. (2002)

Other switches involving participants
SH2 domain-containing adapter protein B (SHB) - 3 more (view)
Lymphocyte cytosolic protein 2 (LCP2) - 2 more (view)

Other switches involving interfaces
SH2 domain - 140 more (view)
ELM:LIG_SH2_IIB - 12 more (view)