Switch #: SWTI000555

Switch type: Binary

Switch subtype: Pre-translational

Description:
Alternative splicing removes the PDZ-binding motif of Isoform 3 of Kinesin-like protein KIF1B (Kif1b), abrogating binding to PDZ domain-containing protein GIPC1 (Gipc1).

Participants:
(1) Isoform 3 of Kinesin-like protein KIF1B (Kif1b)
(2) PDZ domain-containing protein GIPC1 (Gipc1)

(1) Protein interactions with the glucose transporter binding protein GLUT1CBP that provide a link between GLUT1 and the cytoskeleton.
Bunn et al. Mol. Biol. Cell (1999)

Other switches involving participants
PDZ domain-containing protein GIPC1 (Gipc1) - 1 more (view)

Other switches involving interfaces
PDZ domain (Also known as DHR or GLGF) - 45 more (view)
LIG_PDZ_Class_1 - 41 more (view)