Switch #: SWTI000584

Switch type: Binary

Switch subtype: Pre-translational

Description:
Alternative splicing removes the EVH1-binding motif of Xin actin-binding repeat-containing protein 1 (XIRP1), abrogating binding to Protein enabled homolog (ENAH).

Participants:
(1) Xin actin-binding repeat-containing protein 1 (XIRP1)
(2) Protein enabled homolog (ENAH)

(1) Unusual splicing events result in distinct Xin isoforms that associate differentially with filamin c and Mena/VASP.
van der Ven et al. Exp. Cell Res. (2006)

Other switches involving participants
Xin actin-binding repeat-containing protein 1 (XIRP1) - 1 more (view)

Other switches involving interfaces
WH1 domain - 2 more (view)
LIG_EVH1_1 - 1 more (view)