Description: Phosphorylation of S461 in the PP1-binding motif of Neurabin-1 (Ppp1r9a) by cAMP subfamily inhibits binding to the Serine/threonine-protein phosphatase PP1-alpha catalytic subunit (Ppp1ca). Binding of Neurabin-1 (Ppp1r9a) inhibits activity of the phosphatase.
Participants: (1) Neurabin-1 (Ppp1r9a) (2) Serine/threonine-protein phosphatase PP1-alpha catalytic subunit (Ppp1ca)
(1) Regulation of neurabin I interaction with protein phosphatase 1 by phosphorylation.McAvoy et al. Biochemistry (1999)
Other switches involving interfacesDOC_PP1 - 4 more (view)Calcineurin-like phosphoesterase - 5 more (view)
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