Interaction #1 NFATC1 - UBE2I
(1) MOD_SUMO motif (701IKTE704) in Nuclear factor of activated T-cells, cytoplasmic 1 (NFATC1)
(2) Ubiquitin-conjugating enzyme (8-152) in SUMO-conjugating enzyme UBC9 (UBE2I)
Alternative splicing Abrogation of the Nuclear factor of activated T-cells, cytoplasmic 1 (NFATC1) MOD_SUMO motif - SUMO-conjugating enzyme UBC9 (UBE2I) Ubiquitin-conjugating enzyme interaction
(1) Sumoylation of the transcription factor NFATc1 leads to its subnuclear relocalization and interleukin-2 repression by histone deacetylase.
Other switches involving participants