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Group by :Switch typeMotif classProteinEnzymePathway         Hide inferred   Group Index    Colouring Info              Filtered: PFAM:PF00134 (1 hits) x


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          Curated          inferred


x  Index
PKC subfamily ()


MotifProteinStartEndSwitch TypeSwitch SubtypeSwitch descriptionInformationEvidence

PKC subfamily
DOC_CYCLIN_1 AKA12_MOUSE501504BinaryPhysicochemical compatibilityPhosphorylation of S507 adjacent to the cyclin-binding motif of A-kinase anchor protein 12 (Akap12) by PKC subfamily blocks binding to the G1/S-specific cyclin-D1 (Ccnd1). As a result, the function of A-kinase anchor protein 12 (Akap12) as a scaffold is inhibited and G1/S-specific cyclin-D1 (Ccnd1) is translocated to the nucleus where it regulates progression of the cell cycle from G1 to S phase.
details
Curated
           
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