About Help Definitions Submit Search Analyse Browse Home


Group by :Switch typeMotif classProteinEnzymePathway         Hide inferred   Group Index    Colouring Info              Filtered: PFAM:PF01602 (1 hits) x


x  Coloured by: Modifier evidence source
          Curated          inferred


x  Index
PKC subfamily ()


MotifProteinStartEndSwitch TypeSwitch SubtypeSwitch descriptionInformationEvidence

PKC subfamily
TRG_ER_diArg_1 NMDZ1_HUMAN893895BinaryPhysicochemical compatibilityPhosphorylation of S896 adjacent to the ER retention motif of Glutamate [NMDA] receptor subunit zeta-1 (GRIN1) by PKC subfamily (and possibly S897 by PKA) inactivates the motif and promotes delivery of the receptor to the plasma membrane. Optimal trafficking upon dual phosphorylation of S896 and S897 allows regulation of receptor trafficking by coordinated PKA and PKC signaling.
details
Curated
           
Please send any suggestions/comments to: switches@elm.eu.org